Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > PNS receptors and characteristics > Flashcards

PNS receptors and characteristics Flashcards

1
Q

M1

A

Autonomic ganglia
Depolarizes postsynaptic neurons (slow EPSP)
↑ PLC → ↑ IP3, DAG, Ca++

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

M2

A

Heart
↓ Heart rate, conduction velocity, contractility
↓ AC → ↓ cAMP; ↑ K+ channel efflux, ↓ Ca++ channel influx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

M3 in smooth muscle

A

Smooth muscle (eye, bronchioles, GI tract, urogenital system)
Contraction
↑ PLC → ↑ IP3, DAG, Ca++

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

M3 in secretory glands

A

Secretory glands
↑ Secretion
↑ PLC → ↑ IP3, DAG, Ca++

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

NM

A

Neuromuscular junction
Skeletal muscle contraction
Opens Na+/K+ channels → depolarization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

NN in autonomic ganglia

A

Autonomic ganglia
Depolarizes postsynaptic neurons
Opens Na+/K+ channels → depolarization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

NN in adrenal medulla

A

Adrenal medulla
Depolarizes medullary cells → secretion of catecholamines
Opens Na+/K+ channels → depolarization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

a1 in smooth muscle

A

Smooth muscle (eye, vascular, urogenital, hair follicles)
Contracts smooth muscle
↑ PLC → ↑ IP3, DAG, Ca++

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

a1 in liver

A

Liver
↑ Glycogenolysis, gluconeogenesis
↑ PLC → ↑ IP3, DAG, Ca++

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

a2 in axon terminals

A 
Axon terminals (autoreceptors)
↓ NE release
↓ AC → ↓ cAMP; ↑ K+ channel efflux; ↓ L- and N-type Ca++ channel influx; ↑ PLC → ↑ IP3, DAG, Ca++
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

a2 in vascular smooth muscle

A

Vascular smooth muscle
Contracts smooth muscle
↓ AC → ↓ cAMP; ↑ K+ channel efflux; ↓ L- and N-type Ca++ channel influx; ↑ PLC → ↑ IP3, DAG, Ca++

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

a2 in pancreatic B cells

A

Pancreatic B cells
Decreased insulin secretion
↓ AC → ↓ cAMP; ↑ K+ channel efflux; ↓ L- and N-type Ca++ channel influx; ↑ PLC → ↑ IP3, DAG, Ca++

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

a2 in platelets

A

Platelets
Causes aggregation
↓ AC → ↓ cAMP; ↑ K+ channel efflux; ↓ L- and N-type Ca++ channel influx; ↑ PLC → ↑ IP3, DAG, Ca++

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

B1 in heart

A

Heart
Increased contractility, conduction velocity, heart rate
↑ AC → ↑ cAMP → ↑ PKA → ↑ Ca++ channel influx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

B1 in kidney

A

Juxtaglomerular cells
Increased renin release
↑ AC → ↑ cAMP → ↑ PKA → ↑ Ca++ channel influx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

B2 in smooth muscle

A

Smooth muscle (eye, bronchioles, GI, urogenital, vascular)
Relaxes smooth muscle
↑ AC → ↑ cAMP; inhibits smooth muscle MLCK → ↓ myosin-PO4 → relaxation

17
Q

B2 in heart

A

Heart
Increased heart rate, contractility
↑ AC → ↑ cAMP; inhibits smooth muscle MLCK → ↓ myosin-PO4 → relaxation

18
Q

B3

A

Lipocytes
Activates lipocytes
↑ AC → ↑ cAMP

19
Q

D1

A

Vascular smooth muscle, especially renal vasculature
Dilates blood vessels
↑ AC → ↑ cAMP

20
Q

D2

A

Axon terminals (autoreceptors) of cholinergic neurons in the gut
↓ DA release, ↓ GI motility
↓ AC → ↓ cAMP; ↑ K+ efflux; ↓ Ca++ influx

Pharmacology (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions