Pneumonia Flashcards
What is definition of pneumonia
any inflammatory condition affecting alveoli of the lungs - usually secondary to a bacterial infection
What are risk factors for pneumonia
<5 or >65
smoking
recent viral resp tract infection
Chronic respiratory disease
Immunosuppression
Patients at risk of aspiration
IV drug users
diabetes , CVD
What is the most common organism that causes CAP
Streptococcus pneumoniae
What other organisms cause CAP
Haemophilus influenzae
S.aureus
atypical pneumonias -Mycoplasma pneumoniae
viruses
Klebsiella pneumoniae - classically in alcoholics
What is pneumococcal pneumonia and the characteristic features
caused by streptococcus pneumoniae
rapid onset
high fever
pleuritic chest pain
herpes labialis - cold sores
How may someone with pneumonia present
cough with purulent sputum
dyspnoea
chest pain
fever
malaise
signs of systemic infection
tachypnoea
low oxygen sats
reduced breath sounds
What is stepwise investigations for pneumonia
Chest X-ray
- may show consolidation/ effusion
REPEAT 6 WEEKS AFTER CLINICAL RESOLUTION
Bloods
FBC, U&Es,CRP and blood cultures
sputum sample
Test for urinary antigen for Legionella
What investigations might be needed for atypical pneumonia
CT may be needed to detect abcess/empyema formation with bronchoscopy
Mycoplasma serology
What is CURB-65
predicts 30 day mortality in CAP
Confusion
Urea >7
Respiratory rate >30
SBP <90 or DBP<60
65
How do you interpret the scores of CURB-65
0-1- low risk home based care
2- intermediate risk , hospital care
3-5 high risk, intensive care
How do you treat patient with CURB-65 score of 0-1
OUTPATIENT
first line - amoxicillin
if allergic then clarithromycin
5 day course
How do you treat patient with CURB65 score of 2
Dual antibiotic therapy
amoxicillin and clarithromycin \
7-10 day course
How do you treat patients with CURB-65 score >3
consider ITU
Co-amoxiclav AND clarithromycin
7 DAYS
How do you manage hospital acquired pneumonia
Co-amoxiclav
Doxycycline if penicillin allergy
How do you manage atypical pneumonia
Clarithromycin or Doxycycline