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Pmhnp Boards > Pmhnp Boards > Flashcards

Pmhnp Boards Flashcards

1
Q

Metoprolol not to be used with what antidepressants bc risk of hypotension and bradycardia

A

Paxil, fluoxetine, wellbutrin

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2
Q

What meds cause QT prolongation

A

Geodon, seroquel, haldol and citalopram

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3
Q

Least likely to prolong QT interval

A

Ability, Latuda, Zyprexa

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4
Q

Least sedating SSRI

A

Escitalopram and Fluoxetine

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5
Q

Safest SSRI for pts with Heart issues

A

Sertraline, Escitalopram

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6
Q

Mood stabilizer with least weight gain

A

Lamictal

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7
Q

Antipsychotics with least weight gain

A

GAL
Geodon, ability, Latuda

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8
Q

Steven’s Johnson syndrome

A

Lamictal

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9
Q

Black box warning for Tegretol

A

Agranulocytosis and aplastic anemia

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10
Q

Steven Johnson’s syndrome gene and med

A

Tegretol and HLAB-1502 allele
Asians

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11
Q

Antiepileptics such as Tegretol, Topamax, Dilantin well known to do wha?

A

Decrease effectiveness of Oral Contraceptives

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12
Q

Clozaril and carbamazepine (Tegretol) can cause agranulocytosis

A

D/C clozaril/carb - ANC < 1000
D/C “ “ - WBC of 2000-3000 whether or not s/s

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13
Q

Depakote level

A

(50-125) toxicity at 150

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14
Q

Lithium level toxicity

A

> 1.5 or higher = toxicity = STOP
- 1.3 - 1.4 - no s/s = continue to monitor
- 1.3 - 1.4 - w/ s/s = discontinue Lithium

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15
Q

Serum creatine level and why important with lithium?

A

(0.6-1.2)
Creatinine increase (decrease live function) more important d/t lithium toxicity

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16
Q

What med causes Ebstein anomaly and what is it?

A

Congenital heart- Lithium

17
Q

Meds that increase lithium level due to decrease renal clearance

A

NSAIDS, thiazides, ACE inhibitors, lisinopril

18
Q

Safe mood stabilizer for pregnancy

A

Lamictal

19
Q

Addiction

A

Dopamine and GABA

20
Q

Nightmares

A

Norepinephrine

21
Q

ETOH

A

GABA is up-regulated (increase GABA)
NMDA which is a glutamate receptor in the brain is down regulated (decrease activity)

22
Q

Stimulants

A

Catecholamine (dopamine and norepinephrine) serotonin

Pmhnp Boards (2 decks)

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