Pleural disease Flashcards

1
Q

What types of pneumothorax exist?

A
  • Spontaneous pneumothorax
    • Primary: no lung disease
    • Secondary: pre-existing lung disease eg. COPD
  • Traumatic
  • Tension*
  • Iatrogenic eg. Central line insertion
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2
Q

Name two risk factors for pneumothorax

A
  • Young males (6:1), often tall and thin
  • Over 40s: most commonly due to COPD
  • Connective tissue diseases
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3
Q

What sign can occur following rib fractures

A

Flail chest occurs if 2+ fractures occur in the same rib.

Paradoxical movement of flail segment during respiration

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4
Q

Define tension pneumothorax

A

Medical emergency

Pneumothorax + haemodynamic instability

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5
Q

Describe the presentation of pneumothorax

A
  • Sudden onset unilateral pleuritic pain
  • Progressive dyspnoea
  • May develop pallor and tachycardia
  • Tension: additional tachycardia and hypotension
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6
Q

What signs may be seen with tension pneumothorax?

A
  • Respiratory distress:
    • Increased work of breathing
    • Tachypneoa
    • Low oxygen saturations
  • Tachycardia
  • Hypotension
  • On affected side:
    • Absent breath sounds
    • Tracheal deviation away
    • Hyper-resonant on percussion
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7
Q

What should be done if tension pneumothorax is clinically diagnosed?

A

Immediate decompression of the affected side to establish haemodynamic stability

  • Large bore needle (14/16 gauge)
  • Inserted into 2nd intercostal space
  • Mid-clavicular line
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8
Q

What anatomical landmark is used for chest drain insertion?

A

‘Triangle of safety’:

  • Superior: Base of axilla
  • Anterior: Pectoralis major (lateral aspect)
  • Posterior: Latissimus dorsi (lateral aspect)
  • Base: 5th intercostal space
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9
Q

What are the clinical examination findings in pneumothorax? What are the radiological findings?

A
  • Clinical:
    • Tachypnoea
    • Low oxygen saturations
    • Hyperresonance on percussion
    • Reduced or absent breath sounds
  • Radiological:
    • Rim of air: visible visceral pleural edge
    • Loss of lung markings
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10
Q

Outline the management of non-tension pneumothorax

A
  • Smoking cessation
  • Diving and flying advice
  • Primary:
    • Asymptomatic small rim (<2cm): no treatment, avoid strenuous exercise, follow-up imaging to confirm resolution.
    • Symptomatic small rim (<2cm): needle aspiration and admission
    • Symptomatic after aspiration or >2cm: intercostal drain
  • Secondary: Intercostal drain and discharge. Recurrent: pleurodesis
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11
Q

Describe the presentation of pleural effusion

What are the findings on clinical examination?

A
  • May be asymptomatic
  • Dyspnoea, pleuritic chest pain, reduces exercise tolerance
  • History of pneumonia, which may not be resolving
  • On examination:
    • Reduced chest expansion
    • Stony dull percussion
    • Reduced breath sounds
    • Reduced vocal and tactile fremitus
    • Trachial deviation away (if very large)
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12
Q

What are the radiological findings in pleural effusion

A
  • Lower zone opacification
  • Meniscus sign if fluid alone
  • Air fluid level if hydropneumothorax
  • Blunting of costophrenic angles
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13
Q

What are the different types of pleural effusion?

A
  • Serous fluid:
    • Exudate: protein >30 g/L
    • Transudate: protein <30 g/L
  • Haemothorax
  • Empyema: purulent, may be complication of pneumonia
  • Chylothorax: lymph usually due to leakage from thoracic duct after trauma or infiltration by carcinoma
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14
Q

What investigations are needed in suspected pleural effusion?

A
  • Chest X-ray
  • US guided aspiration
    • pH, protein, LDH, microbiology, cytology
  • CT chest
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15
Q

Give 3 causes of transudate effusion

Give 3 causes of exudate effusion

A

Transudate: <30 g/L due to increased capillary hydrostatic pressure

  • Heart failure
  • Liver failure (unable to produce albumin)
  • Renal failure (loss of proteins in glomerulus)

Exudate: >35 g/L due to increased capillary permeability and protein leakage

  • Infection: pneumonia, TB
  • Inflammation: RA
  • Maligancy: primary lung, mesothelioma
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16
Q

What is the Light’s criteria?

A

A tool used to categorise borderline effusions (25-35 g/L of protein) into transudate or exudate.

Exudate if one or more of the following:

  • Pleural fluid:serum ratio of protein >0.5
  • Pleural fluid:serum ratio of LDH >0.6
  • Pleural fluid LDH >2/3 of upper limit of normal
17
Q

Outline the management of pleural effusions

A
  • General: aspiration and drainage (chest drain)
  • Repeat imaging
  • Specific treatment of underlying cause
18
Q

What is the cause of pleural plaques and pleural thickening?

A

Asbestos exposure. Pleural plaques are the commonest physical manifestation of asbestos exposure.

19
Q

Describe the presentation of pleural plaques

A

Plaques are nearly always asymptomatic, further investigation is not indicated.

20
Q

Define pleural plaques

A

Discrete areas of fibrosis usually occurring in the parietal pleura. Overtime can calcify. Benign and not pre-malignant.

21
Q

Define pleural thickening

A

Widespread pleural thickening usually affecting the visceral pleura. Occurs due to scarring, calcification, and/or thickening. Benign and not pre-malignant.

22
Q

List 2 types of primary pleural tumors

A

Mesothelioma: benign or malignant Pleural fibroma: benign Primary pleural lymphoma

23
Q

Where do secondary pleural tumours more commonly originate from?

A

Lung Breast Stomach Lymphoma

24
Q

How does mesothelioma present?

A

Pleural effusion Persistent pleuritic pain Increasing dyspnoea Mesothelioma can occur with light asbestos exposure

25
Q

What is the prognosis of mesothelioma

A

Median survival of 2 years