Pleomorphic Adenoma Flashcards

1
Q

pleomorphic adenoma merupakan tumor yang terdapat pada

A

glandula saliva

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2
Q

sifat pleomorphic adenoma

A

benigna (jinak)

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3
Q

pleomorphic adenoma berasal dari

A

epitelial dan myoepitelial

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4
Q

pleomorphic adenoma mempengaruhi lobus superfisial dari glandula parotid (B/S)

A

benar

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5
Q

etiologi pleomorphic adenoma

A

blm tau tapi erat dengan paparan radiasi

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6
Q

pleomorphic adenoma menyebabkan

A
  • perubahan struktur gen pada sel epitel
  • diferensiasi sel
  • abnormalitas sitogenik
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7
Q

pada Pleomorphic Adenoma, ditemukan juga abnormalitas sitogenik dari kromosom

A

12q 13-15

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8
Q

gambaran mikroskopis pleomorphic adenoma

A
  • mixoid
  • campuran mixoid dan selular
  • dominan selular
  • selular ekstrem
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9
Q

pleomorphic adenoma terdiri dari sel …

A

sel epitel dan sel mesenkimal

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10
Q

sel epitel pada PA terdiri dari

A

sel duktus dan non duktus

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10
Q

sel mesenkimal pada PA terdiri dari

A

chondroid, myxoid, osseus

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11
Q

komponen epitelial membentuk dustus dan kista kecil yang mengandung

A

eosinofilik coagulum

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12
Q

sel yang tampak sebagai sarang selular, lembaran sel, anastomosing cord, foci keratinisasi sel skuamosa, mukus, atau spindel

A

sel epitel

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13
Q

preparat PA tumornya terdapat di glandula

A

submandibula

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14
Q

morfologi sel myoepitel

A
  • angular
  • spindel
  • bulat dengan nukleus eksentrik / sel hyalin
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15
Q

akumulasi material mukoid di sekitar sel myoepitelial memberi pola

A

myxoid

16
Q

degenerasi vakuolar menghasilkan pola

A

cartilagineous-like

17
Q

pada perbesaran lemah pleomorphic adenoma, dijumpai sel-sel yang letaknya satu sama lain agak berjauhan sehingga memberi gambaran seperti

A

tulang rawan