Platelet Ultrastructure Flashcards

1
Q

Contstitutes matrix or muscle and skeletal portion

A

Sol-Gel Zone

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2
Q

Main PL in outer layer

A

Phosphatidylcholine and sphingomyelin

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3
Q

Main PL in Cytoplasm

A

Phosphatidylinositol, phosphatidylethanolamine, phosphatidylserine

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4
Q

Thickness of Glycocalyx

A

20-30 nm

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5
Q

Electrical charge of glycocalyx

A

Negative

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6
Q

It sequesters the Ionic calcium

A

DTS

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7
Q

DTS houses the enzymes:

A

PLA2
CO
TS

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8
Q

GP Ia/IIa other nomenclature

A

a2B1

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9
Q

Ligand of a2B1

A

Collagen

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10
Q

GP Ia/IIa CD

A

CD29, CD49b

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11
Q

Ligand of avB1

A

Vitronectin

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12
Q

Ligand of a5B1

A

Laminin

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13
Q

Ligand of a6B1

A

Fibronectin

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14
Q

GP VI is a member of

A

Ig family

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15
Q

GP VI ligand

A

Collagen

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16
Q

GP IIb/IIIa other nomenclature

A

aIIbB3

17
Q

GPIIb/IIIa CD

A

CD41, CD61

18
Q

Ligand of GP IIb/IIIa

A

vWF, Fibrinogen

19
Q

GP Ib/IX/V ligand

A

vWF, thrombin

20
Q

GP Ib/IX/V CD

A

CD42a
CD42b
CD42c
CD42d

21
Q

Microfilaments is composed of

A

actin

22
Q

Intermediate filaments

A

Desmin and Vimentin

23
Q

P-selectin CD marker

A

CD62

24
Q

FcyIIA CD marker

A

CD32

25
Q

Associated with heparin-induced thrombocytopenia

A

FcyIIA

26
Q

PECAM CD marker

A

CD31

27
Q

Mediates PLT to WBC and PLT to EC adhesion

A

PECAM

28
Q

Assoxiated with Immune reaction and inflammation

A

ICAM ( CD50, CD54, CD102)