Platelet Estimate Flashcards
Platelet
• a vital part of______
• are fragments of the______
hemostasis
megakaryocyte cytoplasm
Platelet
• They are also described to______ to glass surfaces or to debris in the diluting fluid
• They easily______ and are difficult to discriminate from_____
easily attach
disintegrate; debris
Platelet
• platelets are_____ in nature and as a result, they may clump easily
• To decrease this tendency,_____ may be used as an anticoagulant.
Sticky
EDTA
induces a difficulty in performing due to the fact that these cellular fragments are small and difficult to identify.
• Platelet counting
Platelet Estimate:
PLT estimate [× 10^9 /L] = A X 2
A = # of plt counted in 10 fields
A equals the…
the RBCs of which do not overlap with one another
total number of platelets counted in 10 oil immersion fields
______ plateletsp er field are considered normal
• 8-20 platelets
Normal Platelet ranges from
150 to 450 ×10^9/L
is found in thrombocytopenic purpura, some infections, certain acute leukemia, pernicious and aplastic anemia, or when the patient is undergoing radiation treatment of chemotherapy.
Thrombocytopenia
can be found in rheumatic fever, asphyxia, post-surgery, post-splenectomy, acute blood loss and with some types of chemotherapy for leukemia treatment.
Thrombocytosis
thrombocytopenic purpura
Thrombocytopenia
some infections
Thrombocytopenia
certain acute leukemia
Thrombocytopenia
pernicious and aplastic anemia
Thrombocytopenia
patient is undergoing radiation treatment of chemotherapy.
Thrombocytopenia
rheumatic fever
Thrombocytosis
asphyxia
Thrombocytosis
post-surgery
Thrombocytosis
post-splenectomy
Thrombocytosis
acute blood loss and with some types of chemotherapy for leukemia treatment
Thrombocytosis
Main functions of platelet (3)
Hemostasis
Blood coagulation
Clot formation
Process that stops bleeding
Hemostasis
Hemotstasis
Adherence to blood vessels
Platelet plug formation
Release of chemicals form clot
Where platelets come from
Anucleate cells
With granules
Megakaryocyte
Why is EDTA preferred?
Reduces platelet clumping
Preserved integrity if ces
Binds calcium which is necessary for clotting
