Plasticity & functional recovery of the brain after trauma Flashcards

1
Q

What is brain plasticity?

A

The idea that the brain is like plastic how it changes & adapts as a result of experience and new learning

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2
Q

When does the brain experience a rapid growth in synaptic connections?

A

During infancy it peaks at around 15000 synapses per neuron at the ages 2-3

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3
Q

What happens to these synaptic connections as we age?

A

The rarely used connections are deleted whilst the frequently used ones are strengthened

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4
Q

What were the original thoughts on brain plasticity & how has it changed after more recent research?

A
  • Changes to the brain were restricted to the developing brain and an adult brain has a fixed structure & function
  • More research suggests that neural connections can change at any time in life & new connections can form as a result of learning and experience
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5
Q

What research did Mechelli et al do into plasticity?

A

He found a larger parietal cortex in bilingual people’s brain compared to monolingual person’s brain

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6
Q

What happens to unaffected areas of the brain after a physical injury or other forms of trauma?

A

It is able to adapt and compensate for the damaged areas

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7
Q

What is functional recovery?

A

A form of plasticity where the brain is able to redistribute or transfer functions usually performed by the damaged areas after damage through trauma

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8
Q

What do neuroscientists suggest about the process of functional recovery?

A

It can happen quickly after trauma (spontaneous recovery) and then slow down after several weeks or months

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9
Q

What happens in the brain after recovery?

A
  • The brain is able to reorganise itself & form new synaptic connections close to the damaged area
  • Secondary neural pathways that wouldn’t typically be used to carry out certain functions are activated to enable functioning to continue
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10
Q

What are the 3 structural changes that happen in the brain during recovery?

A

Axon sprouting, reformation of blood vessels & recruitment of homologous areas on the opposite side of the brain to perform specific functions

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11
Q

What is axon sprouting?

A

The growth of new nerve endings which connect with other undamaged nerve cells to form new pathways

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12
Q

What is reformation of blood vessels?

A

Damaged blood vessels are reformed to ensure the brain functions in affected areas

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13
Q

Evaluation: Practical application

A
  • Understanding processes in plasticity has contributed to neurorehabilitation
  • Since spontaneous recovery slows down after several weeks/months a form of physical therapy may be required to maintain improvements in functioning
  • Techniques may include movement therapy & electric stimulation of the brain to counter deficits in motor/cognitive functioning from a stroke for e.g.
  • shows that the brain may be capable to ‘fix itself’ to an extent and further intervention needed for success
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14
Q

Evaluation: Negative plasticity

A
  • The brain’s ability to rewire itself may have negative behavioural consequences
  • Prolonged drug use shown to result in poorer cognitive functioning & increased risk of dementia
  • 60-80% of amputees have been known to develop phantom limb syndrome where they experience painful sensations in the missing limb area which are thought to occur due to reorganisation of somatosensory cortex
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15
Q

Evaluation: Age and plasticity

A
  • functional plasticity tends to reduce with age
  • the brain is more likely to reorganise in children as the brain is still changing based on new learning & experiences
  • Ladina Bezzola et al demonstrated how 40 hours of golf training produces reduced movement in pps aged 40-60
  • reduced motor cortex activity observed by fMRI scans compared to control group
  • shows that neural plasticity does continue with age
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16
Q

Evaluation: Support from animal studies

A
  • early evidence of neuroplasticity & functional recovery came from animal studies
  • Hubel & Wiesel’s study involved sewing one eye of a kitten shut & analysing the brain’s cortical responses
  • it was found that the area of the visual cortex associated with the shut eye wasn’t idle but continued to process information from the open eye