Plasticity And Functional Recovery Of The Brain After Trauma Flashcards

1
Q

Define plasticity

A

Refers to the brains ability to physically and functionally adapt and change in response to trauma, learning and experiences

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2
Q

The idea of plasticity opposes what ?

A

The previous theory that there is a ‘critical window’ for synaptic and neuronal connection formation, which occurred during the first 3 years of life, after which no new neuronal connections would be formed

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3
Q

What does learning and new experiences cause ?

A

New neural pathways to strengthen

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4
Q

What happens to neural pathways which are used infrequently

A

They become weak and eventually die

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5
Q

What did Boyke find out about plasticity ?

A

Even at 60+ learning of a new skill ( juggling) resulted in increased neural growth in the visual cortex

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6
Q

What did Kuhn find out about plasticity

A
  • that playing video games for 30+ minutes per day resulted in increased brain matter in the cortex, hippocampus and cerebellum
  • Thus, the complex cognitive demands involved in mastering a video game caused the formation of new synaptic connections in brain sites controlling spatial navigation, planing, decision making etc
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7
Q

What did Kempermann find out about plasticity

A
  • found that rats housed in more complex environments showed an increase in neurones compared to a control group living in simple cages
  • changes were particularly clear in the hippocampus which is associated with memory and spatial navigation
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8
Q

Define functional recovery

A

The ability of the brain to transfer the functions of areas damaged through trauma to other healthy parts of the brain, thus allowing for normal function to carry on

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9
Q

In what three ways does functional recovery happen ?

A
  • equipotentiality
  • axon sprouting
  • stem cells
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10
Q

Explain how equipotentiality enables functional recovery

A

Where secondary neural circuits surrounding the damaged area become active

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11
Q

Explain how axon sprouting enables functional recovery

A

The formation of new synapses and strengthening of axonal connections between damaged and healthy areas

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12
Q

Explain how the use of stem cells enables functional recovery

A
  • stem cells are specialised cels which can become specialised to carry out different types of task
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13
Q

What are the two factors that affect functional recovery ?

A
  • age. Young people have a high ability to recover which declines as we age
  • level of education is positively correlated with speed of recovery from traumatic brain injuries
  • Researcher round that patients with a college education were 7 times more likely to recover from their disability after 1 year compared to those who didn’t finish college
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14
Q

Explain the limits to spontaneous and functional recovery

A
  • although the after trauma the brain activated secondary neural circuits which contribute towards reinstating normal function the brain can only repair itself up to a specific point, after which motor therapy or electrical stimulation is needed to increase recovery rates
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15
Q

A strength of research examining plasticity and functional recovery is the application of the findings to the field of neurorehabilitation. Explain this

A
  • understanding the process of plasticity and functional recovery led to the development of neurorehabilitation
  • this used motor therapy and electrical stimulation of the brain to counter the negative effects in motor / cognitive functions following accidents.
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16
Q

How does Maguire support plasticity and functional recovery

A
  • use MRI to scan the brains of London Taxi drivers and found significantly more volume of grey matter in the posteriori hippocampus
  • an Andrea associated with spatial and navigational skills , compared to a matched control group
  • learning experiences alter the structure of the brain
17
Q

Explain how Danelli’s case study of EB supports plasticity and functional recovery of the brain

A
  • removed large rumour and virtually all of the left hemisphere at young age
  • linguistic abilities disappeared
  • after rehabilitation language abilities started to improve
  • at 17 tested his language and vertically no difference compared to control group