plasticity and functional recovery Flashcards

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1
Q

what is plasticity ao1

A

plastcity refers to the brains apparent ability to change and adapt both physically and functionally.

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2
Q

how many synaptic connections does an age 2-3 year old have

A

15,000 twice as many as an adult brain

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3
Q

what did Maguire et al study

A

studied the brains of London taxi drivers and found significantly more volume of grey matter in the posterior hippocampus than in a matched control group.

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4
Q

what is synaptic pruning

A

as we age, rarely used connections are deleted and frequently used connections are strengthened.

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5
Q

which part of the brain is associated with spatial and navigational skills in humans and other animals

A

the posterior hippocampus

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6
Q

why do taxi drivers have a larger grey matter in their hippocampus

A

as a part of their training London cabbies must take a complex test called ‘the knowledge’ which assesses their recall of the city streets and possible routes (incl all hotels, hospitals etc). it appears that this spatial learning alters the structure of the taxi drivers brains.

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7
Q

what did draganski et al (2006) discover

A

they imaged the brains of medical students 3 months before and after their final exams. learning induced changes were seen to have occurred in the posterior hippocampus and the parietal cortex, presumably as a result of studying for exams

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8
Q

what did mechelli et al (2004) discover

A

found a larger parietal cortex in the brains of people who were bilingual compared to matched monolingual controls.

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9
Q

what is functional recovery of the brain after trauma

A

following physical injury or trauma such as a stroke, unaffected areas of the brain are often able to adapt and compensate for those areas that are damaged.

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10
Q

what happens to the brain during recovery

A

the brain is able to rewire and reorganise itself by forming new synaptic connections close the area of damage

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11
Q

what structural changes in the brain are there

A
  1. axonal sprouting
  2. reformation of blood vessels
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12
Q

what is axonal sprouting

A

axonal sprouting is the growth of new nerve endings which connect with other undamaged nerve cells to form new neural pathways

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13
Q

what is the third structural change in the brain

A

recruitment of homologous areas. this is when a similar area of the brain on the opposite side is used to perform a specific task.

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14
Q

how has there been a practical application of plasticity ao3

A

understanding the processes involved in plasticity has contributed into the field of neurorehabilitation. following illness or injury spontaneous recovery tends to slow down after a few weeks so physical therapy may be required to maintain improvements in functioning.

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15
Q

what was negative plasticity ao3

A

the brains ability to rewire itself can sometimes have maladaptive behavioural consequences. Medina et al (2007) found that prolonged use of marijuana resulted in poorer cognitive functioning as well as an increased risk of dementia later in life.

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16
Q

negative plasticity continued ao3

A

60-80% of amputees have been known to develop phantom limb syndrome. this means that they continue to experience sensations in the missing limb as if it were still there. these sensations are unpleasant and painful and are thought to be due to the cortical reorganisation in the somatosensory cortex that occurs as a result of limb loss (ramachandran & hirstein, 1998). such cortical reorganisation is an example of brain plasticity

17
Q

how is age and plasticity related ao3

A

functional plasticity tends to reduce with age. the brain has a greater ability to reorganise in childhood as it is constantly adapting to new experiences and learning. however landina bezzola et al (2012) found that 40 hours of gold training produced changes in the neural representation of movement in participants aged 40-60. using FMRI the researcher observed reduced motor cortex activity in the novice golfers compared to a control group, suggesting more efficient neural representations after training.

18
Q
A