Placental and Maternal Physiology Flashcards
Which day does the trophoblast invade the endometrium?
Day 7
What decreases contractility of myometrial cells?
Progesterone
Opthalmic changes w/ pregnancy
Cornea thickens
Decreased IOP
Diabetic retinopathy can worsen
Epulis
Hyperplastic lesion of the mouth, similar to the one seen w/ dilantin.
Referred to as pregnancy tumor
Tumor is red and on gigiva
Pregnancy GI changes
Increased risk of GERD Decreased risk of PUD Constipation, impaction, NV Increased portal venous pressure Gallstones
When does morning sickness occur?
first month to 14-16 wks
Hyperemesis Gravidarum
Caused by rapidly rising hormone levels
Extreme N/V
May indicate multiple pregnncy
Urinary changes
Hydeonephrosis is common
Water retention
UTI’s pyelonephritis
Urinary incontinence
Pregnant woman with pyelonephritis must be?
admitted
Hyperventilation in pregnancy leads to?
respiratory alkalosis
Causes renal excretion of bicarb
Physiologic anemia
Caused by increase in volumes and hemodilution.
Normal in pregnant women
Which element is commonly deficient in pregnancy?
Iron
CV changes
Stoke volume, HR increase
BP, PVR decrease
Oxygen consumption increases
Heart muscle mass increases
Uterine blood flow
700ml/min
Coag changes
Hypercoagulable state
Fall in activity of protein C
Resp changes
UR tract stuffiness
Nose bleeds
Increased respirations
Average weight gain
25 - 35 lbs
Common musculoskeletal complaints
Carpal tunnel
Sciatic nerve pain
GnRH and CRH are increased or decreased?
Increased
Pregnancy state hypercortisolism
Caused by increase in CRH and ACTH
Linea nigra and Melasma (pregnancy mask) caused by?
Increased melanocyte stimulating hormone and melanin
Change in sensitivity to ADH?
Less sensitive to ADH in pregnancy
Glucose metabolism change
Insulin resistance and maternal hyperglycemia have negative effects on fetus
Which lipid levels rise in pregnancy?
Triglycerides (300%)
Cholesterol (50%)
