placenta and fetal membrane Flashcards

1
Q

fetal component and maternal component of placenta is derived from

A

fetal- trophoblast and extraembryonic mesoderm (chorionic plate)
maternal- uterine endometrium

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2
Q

changes in beginning of 2nd month

A

secondary and tertirary villi develop and give a radial appearance
( stem villi extend from extraembryonic mesoderm into the cytotrophoblast shell)

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3
Q

surface of villi is formed by

A

synyctium which rest on a layer of cytotrophoblast and covers a core of vascular mesoderm

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4
Q

extraembryonic vascular system

A

capillaries system developing in core of villus come in contact with the chorionic plate and the connecting stalk and makes the extraembryonic vascular system

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5
Q

maternal blood to placenta is delivered by

A

spiral arteries

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6
Q

endovascular invasion

A

erosion of maternal vessels to release blood into the intervillous system is done through endovascular invasion by cytotrophoblast

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7
Q

how endovascular invasion is done?

A

cytotrophoblast released from the ends of villous replace endothelial cells of spiral arteries with hybrid vessels which contains both maternal and placental cells. cytotrophoblast undergo a epithelial to endothelial transition which transform the high resistance small diameter spiral arteries into low resistance more diameter vessels.

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8
Q

chorion frondosum

A

early developmental days the villi surrounds the whole chorion but as pregnancy advances villi on embryonic pole enlarges and expand give rise to chorion frondosum (bushy chorion)

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9
Q

chorion laeve

A

at the aembryonic pole villi degenerate and by third month this side of chorion is smooth known as chorion laeve

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10
Q

decidua basalis

A

the decidua over the chorion frondosum is known as decidua basalis and has decidual cells. also called decidual plate which is tightly connected to the chorion and has lipids and glycogen

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11
Q

decidua capsularis

A

the decidua over the aembryonic layer is decidua capsularis

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12
Q

decidua parietalis

A

the chorion leave comes in contact with uterine wall (decidua parietalis) from opposite sides fuse together and obliterate the uterine lumen

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13
Q

only portion of chorion participating in exchange are

A

chorion frondosum and decidua basalis makes up the placenta

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14
Q

amniochorionic membrane

A

made by fusion of amnion and chorion makes the amniochorion membrane that obliterates the chorionic cavity and ruptures during birth

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15
Q

placenta has 2 components in the beggining of what month

A

4 month
the fetal component made by chorionic plate
and the maternal component made by decidual plate

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16
Q

junctional zone of placental and maternal areas

A

here the trophoblast and decidual cells intermingle

zone is characterized by giant decidual and syncytial cells with amorphous ecm

17
Q

decidual septa? formation in what month

A

4 to 5 months
there are many septas made by the decidua in the intervillous spaces but they are not in contact with the chorionic plate
they have a core of maternal tissue and are covered by syncytial cells so at all times the maternal blood is separated from the fetal tissues of the villi

18
Q

cotyledons

A

decidua septa divide the intervillous space into cotyledons

19
Q

4 layers of placental membrane

A
  1. endometrium covering the fetal vessels
  2. connective tissue making the core of villous
  3. cytotrophoblast
  4. syncytium
20
Q

how the rate of exchange of placenta is increased

A

the endothelial lining of vessels come in close contact with the syncytium which thins the placental membrane

21
Q

how much 02 does fetus extracts

A

20-30 ml of oxygen from maternal blood

22
Q

what is critical to oxygen supply to fetus

A

placental blood flow and depends on delivery not diffusion

23
Q

progesterone is produced by placenta at what month

A

at 4 month to maintain corpus luteum

24
Q

all hormones are produced by in placenta?

A

syncytial trophoblast

25
Q

hormones produced by placenta except progesterone

A

estrogen (estriol)

which maintain the uterine growth and development of mammary glands

26
Q

another hormone produced by placenta other than estrogen and progesterone

A

somatomammotropin hormone which priorities placenta for glucose on mother and that’s why the mother gets diabetogenic also promotes breast development

27
Q

what is present between amnion and and embryonic ectoderm

A

(amnio-ectoderm junction ) primitive umbilical ring

28
Q

what does the umbillical ring contains

A
  1. connecting stalk- allantois and umbillical vessels
  2. yolk stalk - (vitelline duct) contains vitelline vessels
  3. canal connecting the intra and extra embryonic cavities
29
Q

yolk sac is present in

A

chorionic cavity between the amnion and chorionic plate

30
Q

primitive umbilical cord

A

the amniotic cavity enlarges at the expense of chorionic cavity and envelops the connecting and yolk sac stalk crowding them together to form primitive umbilical cord

31
Q

how yolk sac obliterates

A

yolk sac is present in chorionic cavity attached to the umbilical cord through its cord. when the amnion enlarges it attaches to the chorion obliterating chorionic cavity and the yolk sac degenerates