Placement - MCQs

Question 1

What is a working solution of formalin?

Answer 1

10% NBF containing 3.7/4% formaldehyde

Question 2

Why are dye powders considered bad for you?

Answer 2

They are carinogenic

Question 3

What alcohol is used in Oil red O?

Answer 3

Isopropanol

Question 4

What is the normal cell type seen in a pleural fluid?

Answer 4

Mesothelial cell

Question 5

What fixative is used in liquid-based cytology solutions?

Answer 5

Cytolyt > alcohol based fixation for PAP
Air dried for MGG + methanol fixation

Question 6

Why is DAB considered harmful?

Answer 6

Carcinogenic

Question 7

What is commonly used in antigen unmasking solutions?

Answer 7

Citrate buffer

Question 8

What is CEA expressed in?

Answer 8

All adenocarcinomas but especially colorectal cancer

Question 9

What is cytokeratin 7 expressed by?

Answer 9

Adenocarcinomas of the urothelial origin or mucinous ovarian cancer
i.e. renal or gynae adenocarcinomas

Question 10

What is cytokeratin 20 expressed by?

Answer 10

Colon cancer

Question 11

What percentage of breast cancers over express Her2?

Answer 11

Over 20%

Question 12

What is the name of the therapeutic monoclonal antibody which binds to Her2?

Answer 12

Transtuzumab (Herceptin)