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PKPD > PKPD Spring E1 > Flashcards

PKPD Spring E1 Flashcards

1
Q

Debrisoquine

Enzyme, Genetic Variability

A

CYP2D6

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2
Q

Metoprolol

Enzyme, Genetic Variability

A

CYP2D6

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3
Q

Encainide

Enzyme, Genetic Variability

A

CYP2D6

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4
Q

Imipramine

Enzyme, Genetic Variability

A

CYP2D6

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5
Q

Nortriptyline

Enzyme, Genetic Variability

A

CYP2D6

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6
Q

Maprotiline

Enzyme, Genetic Variability

A

CYP2D6

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7
Q

Hydralazine

Enzyme, Genetic Variability

A

N-acetyltransferase NAT 2

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8
Q

Procainamide

Enzyme, Genetic Variability

A

N-acetyltransferase NAT 2

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9
Q

Isoniazid

Enzyme, Genetic Variability

A

N-acetyltransferase NAT 2

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10
Q

Mercaptopurine

Enzyme, Genetic Variability

A

Thiopurine S-methyltransferase (TPMT)

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11
Q

Azathioprine

Enzyme, Genetic Variability

A

Thiopurine S-methyltransferase (TPMT)

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12
Q

Warfarin

Enzyme, Genetic Variability

A

CYP2C9

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13
Q

Omeprazole

Enzyme, Genetic Variability

A

CYP2C19

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14
Q

Esomeprazole

Enzyme, Genetic Variability

A

CYP2C19

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15
Q

Lansoprazole

Enzyme, Genetic Variability

A

CYP2C19

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16
Q

Pantoprazole

Enzyme, Genetic Variability

A

CYP2C19

17
Q

Rabeprazole

Enzyme, Genetic Variability

A

CYP2C19

18
Q

Irinotecan

Enzyme, Genetic Variability

A

Urine diphosphate glucuronyl transferase

19
Q

Drugs that were FDA recalled because sex-related ADE with OT prolongation

A

CATTG - cat ate the triple gecko

Cisapride
Astemizole
Terfensadine
Troglitazone
Grepaflozacin

PKPD (1 decks)

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