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Pharm II Exam II PK/PD and Adjustment > PK/PD and Adjustments > Flashcards

PK/PD and Adjustments Flashcards

1
Q

Beta Lactams
PK/PD:
Adjustment:

A

Pk/PD: Type 2

Adjust: Renally

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2
Q

Which Beta-Lactams have different Adjustments?

A

Penicillinase-Resistant Penicillins

3rd Gen Cephalosporing (Usually Renal)

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3
Q

Glycopeptides
PK/PD:
Adjustment:

A

Type 3

Renal

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4
Q

Tetracyclines
PK/PD:
Adjustment:

A

Type 3

Liver

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5
Q

Fluoroquinolones
PK/PD:
Adjustment:

A

Type 1

Renal

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6
Q

Macrolides
PK/PD:
Adjustment:

A

Type 2 or 3

Liver

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7
Q

Clindamycin
PK/PD:
Adjustment:

A

Type 3

Liver

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8
Q

Metronidazole
PK/PD:
Adjustment:

A

Type 3

Liver

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9
Q

Bactrim
PK/PD:
Adjustment:

A

Type 3

Renal

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10
Q

Aminoglycosides
PK/PD:
Adjustment:

A

Type 1

Renal

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11
Q

Nitrofurantoin
PK/PD:
Adjustment:

A

Type 3

Renal

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12
Q

Oxazolidinones
PK/PD:
Adjustment:

A

Type 2

Liver

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13
Q

Daptomycin
PK/PD:
Adjustment:

A

Type 1

Renal

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14
Q

Streptogramins
PK/PD:
Adjustment:

A

Type 3

Liver

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15
Q

Rifampin
PK/PD:
Adjustment:

A

Type 3

Liver

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16
Q

Fosomycin
PK/PD:
Adjustment:

A

Type 1

None

17
Q

Fidaxomicin
PK/PD:
Adjustment:

A

Type 3

None

18
Q

Type 1 PK/PD

A

24 hour AUC/MIC and Peak (Cmax/MIC)

Max. Concentration

19
Q

Type 2 PK/PD

A

T>MIC

Max. Duration

20
Q

Type 3 PK/PD

A

24 hour AUC/MIC

Max. Amoun

21
Q

Which TB drugs

have LIVER monitoring?

A 
Rifampin
Rifapentine
Rifabutin
Isoniazid
Pyrazinamide
22
Q

Which TB drugs have RENAL adjustments?

A 
Ethambutol
Pyrazinamide
Fluoroquinolones (L)
Aminoglycosides
Capreomycin
23
Q

Which Malaria drugs have RENAL adjustments?

A

A-P

24
Q

Which Malaria drugs have LIVER adjustments?

A 
Chloroquine
A-L
Mefloquine
Doxycycline
Clindamycin

Pharm II Exam II PK/PD and Adjustment (2 decks)

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