pk Flashcards

1
Q

How are the systemic and pulmonary circulation linked?

A

In series

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2
Q

How is the systemic circulation and the arterial circuts connected?

A

In parallel

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3
Q

What is the blood volume called in veins? Arteries?

A

veins: Unstressed volume
(bc it isn’t under high stress)

Arteries Stressed volume (bc it is under high stress)

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4
Q

What is laminar flow? What layer is the fastest?

A

The flow of blood in layers

Fastest: In the center and immobile at the walls

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5
Q

What is turbulent flow?

A

When velocity is high and blood flows through a narrow opening (مطبات هوائية)

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6
Q

What does turbulence do to resistance to flow?

A

Increases it

(makes sense like flying smoothly in an airplane then turbulence all of a sudden)

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7
Q

What are cardiac murmurs and bruits?

A

cardiac murmurs: Sounds of turbulent flow through valves or backflow (remember ossculation)

bruits: Turbulent flow in periphral arteries due to atherosclerotic plaque or narrowed large arteries

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8
Q

What does Reynolds number predict? What is the formula?

A

Turbulence in blood flow

Formula: Re = pDV/n

ρ density of fluid
D diameter of the tube
V is velocity flow
η is viscosity of the fluid.

(Remember renold regins)

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9
Q

What is the law of laplace?

A

T= (pi-po) x r

Po= pressure compressing the vessel (bc initally it is compressed)

Pi= pressure streching the vessel (bc finally it is streched)

(The palace gets a lot of attention and it has a large radius and atmospheric pressure acts on it and a lot of people are inside so pi)

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10
Q

What is the law of laplace in spherical vessels?

A

T=p x r/2

(bc s looks like 2)

(bc the palace is big and long, not just big)

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11
Q

What is the formula for wall stress? (σ)

A

(σ) = Pxr/wt

wt= wall thickness

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12
Q

What is aneurysm?

A

The weaking of the wall of blood vessel and increasing in radius, which thins out the walls, which causes more tension and stress.

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13
Q

What is the difference between the Flow rate and Velocity?

A

Flow rate How much blood is flowing at a certain time.

Velocity How fast the blood is flowing

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14
Q

What is the formula for velocity and flow rate?

A

V= Flow rate/ cross-sectional area

Q= Volume/time

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15
Q

what is the equation for Flow rate (Q) with resistance and pressure gradient? What is another name for flow rate in this case?

A

Q= ΔP/R

ΔP=
Mean arterial pressure - Right arterial pressure

(Flow rate = Cardiac output)

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16
Q

What is the equation for mean cardiac output in systemic circulation?

A

…………………………………………………………………………
(MAP - right arterial pressure)/ Total periphral resistance

Map = Pressure in the aorta

Right arterial p = P2

TPR = Resistance caused by vasoconstriction or dilation

17
Q

What is the Systemic and pulmonary pressure gradient formulas? ΔP

A

Systemic: arterial pressure – right atrial pressure

Pulmonary: Pulmonary arterial pressure – left atrial pressure

18
Q

What is the formula for resistance to flow in both pulmonary and systemic circulations?

A

Systemic: 100 mmHg / CO

Pulmonary: 15 mmHg / CO

19
Q

Which has higher resistance, pulmonary or systemic circulation? Why? What is the ratio of Systemic to pulmonary?

A

Higher: Systemic (bc it pumps blood to the entire body)

Ratio: 1/7

20
Q

What is poiseuille’s law?

A

R = (8ηl) / (pi r^4)

η = viscosity of blood

l = length of blood vessel

r= radius of blood vessel

(like pause so and weird just like the formula)

21
Q

What is poiseuille’s law flow formula?

A

F= ((Pa -Pb) x (π) x r^4)/ (8ηL)

22
Q

What is the formula for resistance in parallel and series?

A

Parallel: 1/R = 1/R + 1/R..

Series: R = R + R + R……