PK Flashcards
1
Q
Efficacy outcome measurement for B-lactams
Post antibiotic effect
A
Time that free drug concentration remains above MIC
None for gram negative, except for carbapenems
2
Q
fT>MIC
A
Amount of time in interval drug level is above MIC
3
Q
Best PK measurement for fluoroquinolones
A
fAUC(0-24)/MIC ratio
4
Q
Bets PK measure for aminoglycoside
A
PEAK/MIC ratio (8-10/1)
5
Q
Prospective data showed 400-600 AUC/MIC levels of vanc
A
Were not associated with lower treatment efficacy, were associated with increase in kidney injury
6
Q
Memorize table to PK/PD
A
7
Q
Equation for fT>MIC for B-lactams
A
8
Q
A
