Pituitary gland (M1B1) Flashcards

1
Q

secretion when cells may produce molecules that act on themselves or on
cells of the same type is called?

A

autocrine

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2
Q

another term for pituitary gland?

A

hypophysis

hypo: under
physis: growth

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3
Q

The oral component arises as an outpocketing of ectoderm from the
roof of the primitive mouth and grows cranially, forming a structure called?

A

hypophyseal pouch

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4
Q

pituitary consists of two glands which are?

A

posterior neurohypophysis and the anterior adenohypophysis

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5
Q

posterior neurohypophysis consists of?

A

pars nervosa and infundibulum

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6
Q

anterior adenohypophysis consists of?

A

pars distalis, pars intermedia, pars tuberalis

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7
Q

pituitary gland is attached to the hypothalamus region in the brain by?

A

infundibular stalk

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8
Q

which week does hypothyseal pouch form?

A

3 weeks

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9
Q

when does the hypothyseal pouch separates itself from the oral cavity?

A

2nd month

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10
Q

Pituitary gland is formed within the?

A

9th week

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11
Q

the median eminence and the infundibular stalk gets supplied by?

A

superior hypophyseal arteries

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12
Q

superior hypophyseal arteries divide into a?

A

primary plexus

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13
Q

hypothalamic-hypophyseal portal system is the sys of capillaries and veins around the pituitary

A

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14
Q

pars distails accounts for how much of the mass of the anterior pituitary gland?

A

75%

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15
Q

pars distalis contains two types of parenchymal cells with different staining affinities which are?

A
  • Chromophils are secretory cells in which hormones are stored in the cytoplasmic granules. They are also called basophils and acidophils based on their affinities for acid and base dyes.
  • Chromophobes are pituitary cells that by light microscopy lack stainable cytoplasmic secretory granules and represent degranulated chromophils, inactive reserve cells and undifferentiated stem cells.
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16
Q

what colors are basophilic and acidophilic?

A

basophilic > blue

acidophilic > red

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17
Q

Acidophil Cell Subtypes are?

A
  • Somatotrophs which secrete growth hormone (somatotropin)

* Lactotrophs which secrete prolactin

18
Q

Basophilic Cell Subtypes are?

A
  • Corticotrophs: secrete polypeptide hormones which are adrenocortical trophic hormone (ACTH) and B-lipoprotein (B-LPH)
  • Gonadotrophs: secrete 2 different glycoproteins follicle-stimulating hormone (FSH) and luteinizing hormone (LH)
  • Thyrotrophs: secrete thyroid stimulating hormone (TSH)
19
Q

which cell is the most abundant and which one is the least abundant

A

somatotrophs most, thyrotrophs least

20
Q

The activities of the cells of the anterior pituitary are controlled primarily by?

A

peptide-related hypothalamic hormones

21
Q

anterior pituitary secretes 6 major tropic hormones which are?

A
  • Growth hormone
  • Adrenocorticotrpic hormone (ACTH)
  • Thyroid-stimulating hormone (TSH)
  • Prolactin (PRL)
  • Follicle-stimulating hormone (FSH) and Luteinizing hormone (LH): gonads
22
Q

Pars Distalis Functional Activities

A
  • regulate almost all other endocrine glands
  • ovarian function and sperm production
  • milk production
  • the metabolism of muscle, bone, and adipose tissue
23
Q

a narrow zone lying between the pars distalis and pars nervosa is the?

A

pars intermedia

24
Q

anterior pituitary, is one of the two lobes of the pituitary gland that controlled by the?

A

hypothalamus

25
a hormone made by the hypothalamus in the brain and stored in the posterior pituitary gland. It tells your kidneys how much water to conserve?
antidiuretic hormone (ADH) aka vasopressin
26
hormones produced in the neurohypophysis?
ADH and oxytocin
27
in neurohypophysis, ADH and oxytocin are stored in?
neurosecetory bodies/Herring bodies
28
The neurosecretory bodies contain granules with either oxytocin or ADH bound to carrier proteins called?
neurophysin I and II
29
ADH is released in response to inc blood tonicity sensed by?
osmoreceptor cells
30
anterior pituitary gland is connected to the brain by?
short blood vessels
31
secretion from posterior pituitary is controlled by nerve signals that originate in the hypothalamus.
...
32
posterior pituitary gland is actually part of the brain and it secretes hormones directly into the bloodstream under the command of the brain
...
33
long distance signaling, low signaling, involves small molecules and steroids is called?
endocrine ex. insulin, glucoagon
34
what provides blood mainly to the neurohypophysis?
inferior hypophyseal arteries
35
vascular portal sys carrying small regulatory peptide from the hypothalamus to the adenohypophysis is called?
hypothalamic-hypophyseal tract
36
anterior pituitary is controlled by hormones called? through what are they released?
- hypothalamic releasing and hypothalamic inhibitory hormones - hypothalamic-hypophysial portal vessels
37
present in neurohypophysis are highly branched glial cells called?
pituicytes
38
most abundant cell type in the posterior pituitary is the?
pituicytes
39
Posterior pituitary function can be adversely affected by heritable mutations in the gene for vasopressin (ADH)-neurophysin, by compression from a tumor in adjacent tissues, and by head trauma. By lowering levels of vasopressin, such conditions can produce diabetes insipidus, a disorder characterized by inability to concentrate urine, which leads to frequent urination (polyuria) and increased thirst (polydipsia).
...
40
most of the cells of the pars tuberalis | are?
gonadotrophs