Pituitary gland (M1B1) Flashcards
secretion when cells may produce molecules that act on themselves or on
cells of the same type is called?
autocrine
another term for pituitary gland?
hypophysis
hypo: under
physis: growth
The oral component arises as an outpocketing of ectoderm from the
roof of the primitive mouth and grows cranially, forming a structure called?
hypophyseal pouch
pituitary consists of two glands which are?
posterior neurohypophysis and the anterior adenohypophysis
posterior neurohypophysis consists of?
pars nervosa and infundibulum
anterior adenohypophysis consists of?
pars distalis, pars intermedia, pars tuberalis
pituitary gland is attached to the hypothalamus region in the brain by?
infundibular stalk
which week does hypothyseal pouch form?
3 weeks
when does the hypothyseal pouch separates itself from the oral cavity?
2nd month
Pituitary gland is formed within the?
9th week
the median eminence and the infundibular stalk gets supplied by?
superior hypophyseal arteries
superior hypophyseal arteries divide into a?
primary plexus
hypothalamic-hypophyseal portal system is the sys of capillaries and veins around the pituitary
…
pars distails accounts for how much of the mass of the anterior pituitary gland?
75%
pars distalis contains two types of parenchymal cells with different staining affinities which are?
- Chromophils are secretory cells in which hormones are stored in the cytoplasmic granules. They are also called basophils and acidophils based on their affinities for acid and base dyes.
- Chromophobes are pituitary cells that by light microscopy lack stainable cytoplasmic secretory granules and represent degranulated chromophils, inactive reserve cells and undifferentiated stem cells.
what colors are basophilic and acidophilic?
basophilic > blue
acidophilic > red
Acidophil Cell Subtypes are?
- Somatotrophs which secrete growth hormone (somatotropin)
* Lactotrophs which secrete prolactin
Basophilic Cell Subtypes are?
- Corticotrophs: secrete polypeptide hormones which are adrenocortical trophic hormone (ACTH) and B-lipoprotein (B-LPH)
- Gonadotrophs: secrete 2 different glycoproteins follicle-stimulating hormone (FSH) and luteinizing hormone (LH)
- Thyrotrophs: secrete thyroid stimulating hormone (TSH)
which cell is the most abundant and which one is the least abundant
somatotrophs most, thyrotrophs least
The activities of the cells of the anterior pituitary are controlled primarily by?
peptide-related hypothalamic hormones
anterior pituitary secretes 6 major tropic hormones which are?
- Growth hormone
- Adrenocorticotrpic hormone (ACTH)
- Thyroid-stimulating hormone (TSH)
- Prolactin (PRL)
- Follicle-stimulating hormone (FSH) and Luteinizing hormone (LH): gonads
Pars Distalis Functional Activities
- regulate almost all other endocrine glands
- ovarian function and sperm production
- milk production
- the metabolism of muscle, bone, and adipose tissue
a narrow zone lying between the pars distalis and pars nervosa is the?
pars intermedia
anterior pituitary, is one of the two lobes of the pituitary gland that controlled by the?
hypothalamus