Pituitary CIS Flashcards
1
Q
hypopituitarism- 2 subtypes
A
- mass lesions (hypothalamus, pit)
- w/o mass lesions:
- congenital isolated hypogonadotropic hypogonadism
- acquired hypopituitarism
- sheehan syndrome
- funcitonal hypopituitarism
2
Q
congenital isolated hypogonadtropic hypogonadism
A
- occurs in genes that cause prod of GnRH, LH, FSH:
- unnamed (many diff mutations)
- Prader Willi syndrome
- Kallmann syndrome
- occurs with congenital adrenal hypoplasia
3
Q
Kallmann syndrome
A
- 1/3 have def in GH
- dec sense of smell
4
Q
Prader Willi syndrome
A
- insatiable appetite
- prone to emotional outbursts
- small hands and feet
- intellectual disabilities
5
Q
prolactinoma- tx?
A
dopamine agonist
- cabergoline
- bromocriptine
6
Q
prolactinoma- can also suppress what?
A
testosterone (low libido, sexual fxn)
-replace the testosterone!
7
Q
Diabetes insipidus (ADH Def)- tx?
A
- desmopressin nose spray (DDAVP)
- MRI- rule out mass in post pit
8
Q
Diabetes insipidus- if pt cant drink water, what would happen?
A
- dehydrated
- severe hypernatremia!!
9
Q
inc release of GH- pt at risk for?
A
- diabetes
- osteoporosis
- gonadal dysfxn
- Heart dz
- GI cancer
- colyn polyps
10
Q
after transsphenoidal approach- do what in postop period?
A
-replace corticosteroids!
