PID Intro to antibiotics

Question 1

Define what an antibiotic is

Answer 1

An antibiotic is a chemical substance that is produced by microorganisms and has capacity to inhibit growth of or kill other microorganisms
An antimicrobial/bacterial is of natural or synthetic origin that will inhibit growth of/kill bacteria but no harm to host

Question 2

What is therapeutic use of antibiotics?

Answer 2

Therapeutic use is when diseased animals are treated to cure infection

Question 3

What is non-therapeutic use of antibiotics?

Answer 3

Nontherapeutic includes prophylactic, metaphylactic, and growth promotion use. Prophylactic use is preventing disease in healthy animals, metaphylactic use is when diseased herds are treated to cure infection in some individuals while preventing infection in others. Growth promotion use is when animals are given low concentrations to improve growth rate and improve reproductive performance

Question 4

What drugs are effective against non-penicillase producing gram positive cocci? (enterococcus, staphylococcus and streptococcus)

Answer 4

Penicllins, aminopenicillins

Question 5

What drugs have no effect against non-penicillase producing gram positive cocci? (enterococcus, staphylococcus and streptococcus)

Answer 5

Metronidazole

Question 6

What drugs are effective against penicillase-producing staphylococcus?

Answer 6

Amoxicillin, Cephalasporins, Sulfonamides,

Question 7

What drugs are ineffective against pencillase-producing staphylococcus?

Answer 7

Penicillins, Aminopenicillins

Metronidazole

Question 8

What drugs are effective against glucose-fermentative gram negative rods?
(escheria, enterobacter, klebsiellsa, proteus, posturella)

Answer 8

Amoxicillin, Cephalosporins, Sulfonamides, Aminoglycosides, Fluoroquinolones

Question 9

What drugs are ineffective against glucose-fermentative gram negative rods?
(escheria, enterobacter, klebsiellsa, proteus, posturella)

Answer 9

Metronidazole, Penicillins, Lincosamides, Macrolides

Question 10

What drugs are effective against anaerobes?

actinomyces, clostridium, peptostreptococcus, bacteroides, fusobacterium, poryphyromonas, prevotella

Answer 10

Penicillin, Aminopenicillins, Lincosamieds, Metronidazole

Question 11

What drugs are ineffective against anaerobes?

actinomyces, clostridium, peptostreptococcus, bacteroides, fusobacterium, poryphyromonas, prevotella

Answer 11

Aminoglycosides

Question 12

Which drugs inhibit cell wall synthesis?

Answer 12

penicillins

Question 13

Which drugs inhibit protein synthesis?

Answer 13

tetracyclins

Question 14

Which drugs inhibit DNA synthesis?

Answer 14

fluorquinolones

Question 15

Which drug inhibits cell membrane integrity?

Answer 15

colistin

Question 16

Which drug inhibits metabolic processes?

Answer 16

sulfonamide

Question 17

Beta Lactams

Answer 17

Penicillins: amoxicillin, ampicillin, penicillin
Cephalosporins: Cefalexin, Cefpodoxime, Cefvocein
Carbapenems: Impipenem, etrapenem

**Carbapenems not use in vet med along with oxazolidinones and glycopeptides

Question 18

Tetracyclines

Answer 18

Tetracycline, oxytetracycline, doxycycline, doxycycline

Question 19

Macrolides

Answer 19

Erythromycin

Tiamulin

Question 20

Lincosamides

Answer 20

Lycomycin

Question 21

Quinolones

Answer 21

Oxonolic acid, Enrofloxacin, Pradofloxacin

Question 22

Aminoglycosides

Answer 22

Streptomycin
Gentamicin/neomycin
Amikacin

Question 23

Sulfonamides

Answer 23

Sulfadiazine, Trimethroprim

Question 24

Phenicols

Answer 24

Chloramphenicol

Florifenicol

Question 25

Polypeptides

Answer 25

Colistin/Polymixin

Question 26

Miscellaneous

Answer 26

Metronidazole