PICU/ER Flashcards
What type of shock do you suspect if there is evidence of low systemic vascular resistance (SVR) and maldistribution of blood flow (i.e. vasodilation and warm skin)?
Distributive shock
Name three commonly cited examples of distributive shock?
- Sepsis
- Anaphylaxis (causing loss of vasomotor tone)
- Neurogenic/ spinal cord injury (causing loss of vasomotor tone)
When do you suspect cardiogenic shock?
Suspect cardiogenic shock when there are signs of poor perfusion and pulmonary or systemic venous congestion (i.e. increased WOB, grunting respirations, distended neck veins, hepatomegaly)
What vasopressors do you want to use when you have a patient who is in hypotensive vasodilated (WARM) shock?
Norepinephrine
[OR high dose dopamine (10-15) OR high dose epinephrine (0.1-0.3)]
What vasopressors do you want to use when you have a patient in hypotension vasoconstricted (COLD) shock?
Low dose Epinephrine (0.01 - 0.1)
[low dose dopamine (5-10) could also work]
What vasopressor is the agent of choice for a child with fluid-refractory septic shock who presents with impaired perfusion but adequate blood pressure
Dopamine
What does dopamine do at low, intermediate, and high doses?
Low dose = improves splanchnic and renal blood flow
Intermediate dose = improves cardiac contractility
High dose = SVR is increased
Name 4 examples of obstructive shock
- Ductal-dependent (LV outflow tract obstruction)
- Tension pneumothorax
- Cardiac tamponade
- Pulmonary embolism
What should your CPR rate be? (# of chest compressions per minute)
At least 100 per minute
What should the depth of your chest compressions be?
At least 1/3 of the AP diameter (2 inches in children, 1.5 inches in infants)
When should you rotate compressors during CPR?
Rotate compressors every 2 minutes
How long should pauses be during CPR?
Minimize and attempt to limit pauses to less than 10 seconds
What is the ratio of chest compressions and breaths for CPR?
For children and infants, you provide 30 compressions: 2 breaths for single rescuer and 15 compressions: 2 breaths for more rescuers
With an advanced airway, how often do you give breaths during CPR?
1 breath every 6-8 seconds
Breaths should last for 1 second, and look for chest rise
When should you start thinking of the possible need for vasopressors or stress-dose hydrocortisone?
They should be immediately available if the shock is fluid refractory or adrenal insufficiency is suspected
What is the role of vasopressin in the sepsis PALS algorithm?
Vasopressin infusion may be useful in the setting of norepinephrine-refractory shock. Vasopressin antagonizes the mechanisms of sepsis-mediated vasodilation. It acts synergistically with endogenous and exogenous catecholamines in stabilizing BP but it has no effect on cardiac contractility
If you are managing a child under the sepsis algorithm and you are considering that the child is adrenally insufficient (fluid-refractory and dopamine- or norepinephrine- dependent shock), how will you manage?
- Draw baseline cortisol
2. Give IV hydrocortisone 2 mg/kg bolus (max: 100 mg)
What is the mainstay/ first-line treatment for anaphylaxis?
IM Epinephrine (1:1000) 0.01 mg/kg
What are other (less important) treatments in the management of anaphylaxis?
- Antihistamine (H1 blocker like Benadryl or H2 blocker like Ranitidine or Famotidine)
- Corticosteroids (Prednisone or Methylpred)
- Salbutamol (Ventolin)
- Trendelenburg position
Why is milrinone often the preferred drug of choice when dealing with children with cariogenic shock?
Milrinone (a phosphodiesterase enzyme inhibitor) will improve contractility (increase cardiac output) and will reduce peripheral vascular resistance (decrease afterload)
What mL/kg fluid boluses should be administered in a child you are wondering may be in cardiogenic shock?
5 to 10 mL/kg NS bolus over 10-20 minutes, repeat PRN
What is the specific management for a tension pneumothorax?
Needle decompression followed by tube thoracostomy
What is the pathophysiology of a duct-dependent lesion?
Ductal-dependent pulmonary blood flow:
- Severe obstruction to pulmonary blood flow form the R ventricle, so all the pulmonary blood flow comes from the aorta through the PDA
- When ductus closes, the infant becomes profoundly cyanotic and hypoxemic
Ductal-dependent systemic blood flow:
- Obstruction to the outflow through or from the left side of the heart into the aorta
- Systemic blood flow comes from the R ventricle and pulmonary artery into the aorta
- When ductus closes, the child has poor systemic perfusion + shocky
What is the mainstay treatment for a child in obstructive shock due to a ductal-dependent lesion?
Continuous infusion of prostaglandin E1 (PGE1)
What sites should be used for an IO?
Proximal tibia
- Identify the tibial tuberosity, the site should be 1-3 cm below and medial to the bony prominence
Other sites: distal tibia just above the medial malleolus, distal femur, ASIS