picu Flashcards
oxygen delivery (equation)
cardiac output x oxygen content
cardiac output (equation)
HR x SV
oxygen content (equation)
(1.34 x hgb x SpO2) + 0.003 x PaO2
hypovolemic shock - what kind of problem?
preload
hypovolemic shock symptoms
hypotension, tachycardia, dehydration, poor perfusion
hypovolemic shock tx
fluids!
cardiogenic shock - what kind of problem?
contractility
cardiogenic shock symptoms
hypotension, tachycardia, tachypnea, lung crackles, hepatomegaly, cool expremities, depressed mental status, WORSENS with fluids
SIRS criteria
temp (< 36 or > 38)
HR
RR
WBC (< 4 or > 12)
SIRS: HR by age (neonate, infant, 1-5, 6-13, 12-18)
neonate < 100 or > 180
infant < 90 or > 180
1-5 yrs > 140
6-12 yrs > 130
13-18 yrs > 110
SIRS: RR by age (neonate, infant, 1-5, 6-13, 12-18)
neonate > 50
infant > 34
1-5 yrs > 22
6-12 yrs > 18
13-18 yrs > 14
monitoring shock
HR, BP, mental status, UOP, lactate, SVO2, pulses, perfusion
SvO2
normal = 25 below arterial
- high = failure of energy usage
- low = excess oxygen demand, inadequate delivery
brain death exam
loss of the following reflexes:
- pupils
- cornea
- bulbar musculature
- cough, gag, suck, root
- oculovestibular
apnea test: absence of respiratory effort with PaCO2 > 60 and > 20 above baseline i/s/o normal pH, PaCO2, BP, temp prior
brain death definition
cessation of neuro function of brain due to known, irreversible cause. clincial dx.
cerebral perfusion pressure
MAP - ICP
neuroprotection goals:
- CO2
- glucose
- sats
- temp
- Na
- CO2: 35-40 (hypocarbia –> vasoconstriction)
- glucose: 80-180
- sats: > 92%
- temp: low normal`
- Na: > 140
improving oxygenation on a vent
- FiO2
- MAP (PEEP and I time)
improving ventilation on a vent
minute ventilation = RR x TV
lung protection in ARDS
- low TV 4-6 mL/kg
- high PEEP 8-12
- allow hypercarbia (to pH > 7.25) and hypoxemia (sats > 88%)
meds for status asthmaticus
- albuterol
- steroids
- magnesium
- IM epi
- terbutaline
- atrovent
- heliox
- aminophyline
albuterol MOA + side effects
- B2 agonist
- tachycardia, tremor, agitation, hypoK
terbutaline MOA + side effects
- B2 agonist
- tachycardia, tremor, agitation, hypoK, myocardial ischemia (get EKG prior)
epinephrine MOA
- B2 agonist
steroids MOA + side effects
- decrease inflammation and mucous production
- GI ppx, bradycardia
atrovent MOA + side effects
- anticholingeric (inhibits cGMP)
- minimal evidence outside ED
heliox MOA + side effects
- promotes laminar flow and decreases airway resistance
- cant use if requiring > 40% fiO2
Mg MOA + side effects
- smooth muscle relaxation via calcium channel blocker
- hypotension
aminophyline MOA + side effects
- unknown MOA of smooth muscle relaxation
- jitteriness, irritability, n/v
complications of central line placement
bleeding, infection, clotting, arrhythmia, pneumo, arterial puncture
ETT placement
breath sounds, chest rise, condensation in tube, ET CO2, CXR