Physiology sex, pregnancy and lactation Flashcards
Most important source of sensory nerve signals for initiating the male sexual act.
Glans penis
Special modality of sensation
Exual sensation
S2, S3, S4
Pudendal nerve- sacral plexus- sacral portion of SC
Impulses may also enter the SC from areas adjacent to the penis
Anal epithelium
Scrotum
Perineal structures
First effect of male sexual stimulation
Penile erection
Degree of ercetion is proportional to the degree of stimulation wheather
Psychic
Physical
Male
Erection- orgasm- resolution
Facidity of penis after orgasm
Detumescence
The entire period of emission and ejaculation is called the
Male orgasm
At its termination, the male sexual excitement disappears almostentirely within 1-2 minutes and erection cease
Resolution
Successful performance of the female sexual act depends on both
Psychic stimulation
Sexual stimulation
Especially sensitive for initiating sexual sensations
Clitoris
Lead to erectile tissue
Genital tubercle
Female, lubrication
Bilateral bartholin glands
Vaginal epithelium
Vaginal epithelium
Stratified squamous
Wet mucosa
Age and menopause
Dry vagina
Sexual stimulation and psychic conditioning reaches maximum
Female orgasm or climax
Reflexes increase uterine and fallopian tube motility during the
Orgasm
Can fascilitate the meeting of egg and sperm
More on physical
More on psychic
Male
Female
One germ cell ( oocyte)
Surrounded by endocrine cells
Single ovarian follicle
Cells in ovarian follicle
Granulosa cell
About every 28 days, gonadotropic hormones from the anterior pituitary cause about how many new follicles to begin to grow in the ovaries
8-12
But only 1 persist to become dominant follicle or graffian follicle
Primary oocyte
Graffian follicle
The mature ovum surrounded by the
Corona radiata
Ovum fertilization
Mature ovum surrounded by corona radiata Dispersal of corna radiata Entry of the sperm Fromation of male and female pronuclei Reorganization of full complement of chromosomes and beginning division of the ovum
Excess
Pola bodies
4 sperm
1 spermatocyte
1 eggcell
1 oocyte
1 egg is to 1 sperm
No other sperm can penetrate
Acrosome reaction
Granulosa cells attached to the outside of the ovum
Corona radiata
Before a sperm can enter the ovum, it must first penetrate the multiple layers of
Corona radiata
Zona pellucida
3-4 days
Blastocyst
5 days
Implantation
Location that stay sperm and egg
Ampulla
Steps in ovulation to implantation
Ovulation
Fertilization of the ovum in the fallopian tube
Implantation of the blastocyst in the uterus
Action of trophoblast cells in implantation of the blastocyst in the uterine endometrium
Before implantation, the blastocyst obtain its nutrition from the uterine endometrial secretion
Uterine milk
Implantation of blastocyst
Invasion of cyto and syncitiotrophoblast
Formation of syncitiothropoblast
Placental formation
Extra
Molar pregnancy
Kiawa
When conceptus implants in the endometrium
Continued secretion of progesterone
Endometrial cell swelling and storage of more nutrients
Endometrial cell swelling
Decidual cells
Only means of nutrition during 1st week until 7 weeks ( some of nutition)
Trophoblast cells invade the decidua
Placenta also begins to provide nutrition after
16th day beyond the fertilization
A little more than 1 week after implantation
Early nutrition
Trophoblast/ endometrium decidua
Later nutrition
Placental membrane
The source of blood of trophoblast
Spiral arteries
Spiral arteries are from the
Uterus
White s balot
Allantois
Function of the placenta
Nutrition
O2 and CO2 exchange
Fetal kidney
Endocrine gland
In pregnancy, the placenta forms especially large quantities of the ff
HCG
Estrogen
Progesterone
Human Chorionic Somatomammotrophin
Secreted by the syncytial trophoblast cells into the fluids of the mother
HCG
HCG first appears in maternal blood
7-9 days post fertilization
HCG peaks at
8-10 weeks
HCG gradually falls to plateau at
18-22 weeks
Serum HCG
More accurate
Urine HCG
8-10 weeks
Mas uunang tumaas ang HCG kaysa s estrogen at progesterone
True
Scar in the ovary
Corpus albican
Prevents involution of the corpus luteum at the end of the monthly female sexual cycle
HCG
If CL is removed before approximately the 7-12 week
Spontaneous abortion almost always occur
Secretes sufficient quantities of progesterone and estrogen to maintain pregnancy
Placenta
CL involutes slowly after the
13-17 week of gestation
HCG produce _________ in male fetuses
Testicular estrogen
Estrogens function in mother
Enlargement of uterus
Enlargement of breast
Enlargement of female external genitalia
Relax the pelvic ligaments
Woman with high adipose
More estrogen
Late menopause
Strong bones
Risk in uterine cancer
Non pregnant
Estradiol
Ovary
Pregnancy
Estriol
Placenta
Fetal adrenal- original source
After menopause
Estrone
Adipose
Relaxing hormone
Progesterone
Causes decidual cells to develop in the uterine endometrium
Progesterone
Progesterone functions
Decrease contractility of pregnant uterus
Also in GIT and GUT
Progesterone helps the estrogen prepare the mothers
Breast for lactation
Progesterone increase the secretion of the mothers fallopian tubes and uterus to provide appropriate nutritive matter for the developing
Morulla
Human chorionic somatomammotropin
Placenta 5th week
Proportion to the weight of placenta
HCS formerly known as
Human placental lactogen
HCS weak action similar to those of
Growth hormone
HCS is diabeticogenic hormone for pregnancy
Making a larger quantities of glucose in fetus
Maternal adaptations to pregnancy
Increased basla metabolic rate 15%
Increased COP
Increased ventilation
Increased RBF and GFR
Progesterone increased respiratory centers sensitivity to CO2
Increased minute ventilation
Physiologic weight gain
1st, 2nd & 3rd trimester
2, 11, 11 lbs
Highest peak of cardiac load
28 week
Increased flow to heart from uterine squeezing, increased HR due to labor pains
During labor
Due to increased venous return
Immediately after labor
Mobilization of interstitium
During 1st week of puerperium
More fluid in the body
Dilutional anemia
State of vasodilation
Smooth muscle relaxation
Pregnancy
Maternal adaptations to pregnancy
Increased lahat maliban s
Total peripheral resistance Total pulmonary resistance Serum creatine Hematocrit Platelet count IOP Sodium and potassium
Maternal adaptations to pregnancy
No change
Systolic blood pressure
Lung compliance
Nirth of the baby
Parturition
Intense contractions responsible for parturition due to
Progressive hormonal changes
Progressive mechanical changes
From implantation to few weeks before delivery
Prelude to paturition
Quiescence
Phase 0
Last 6-8 weeks of pregnancy
Preparation for labor
Activation
Phase 1
Active labor, stage 1-3
Process of labor
Stimulation
Phase 2
Puerpeium
Maternal recovery from birth
Parturient recovery
Involution
Phase 3
Hormone in phase 0
Progesterone
Prostacyclin
Relaxin
Nitric oxide
Phase 1
Estrogen
Progesterone withdrawal
Phase 2
Oxytocin
Prostagalndin
Serotonin
Histamine
Phase 3
Oxytocin
Strethching of uterine cervix lead to
Paraventricular and supraoptic secretion of oxytocin
Labor is prolonged in
Hypophysectomized animals
Prostaglandin E
Cytotec
Ripening the cervix