Physiology of Vision Flashcards

1
Q

Fibrous outer layer

A

Sclera and Cornea

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2
Q

Vascular middle layer

A

Iris, ciliary body, choroid

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3
Q

Neural inner layer

A

Retina

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4
Q

Aqueous humor is needed because…

A

It gives nutrients to the lens and cornea

It creates refractive power to the eye

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5
Q

What is the image formation based on?

A

The combined refractive power of the cornea, aqueous humor, lens and vitreous body

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6
Q

What is the main function of the lens?

A

To provide a refractive power that can be adjusted

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7
Q

Convex or concave lens?

A

Convex lens

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8
Q

Distant vision, ciliary muscle…

A

Relaxes

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9
Q

The accommodation reflex definition

A

A reflex action of the eye, in response to focusing on a near object, then looking at a distant object (and vice versa), comprising coordinated changes in vergence, lens shape and pupil size (accommodation).

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10
Q

The Accommodation Reflex pathway

A

Information from the light on each retina is taken to the occipital lobe via the optic nerve and optic radiation (after a synapse in the lateral geniculate body of the posterior thalamus), where it is interpreted as vision. The peristriate area 19 interprets accommodation, and sends signals via the Edinger-Westphal nucleus and the 3rd cranial nerve to the ciliary muscle, the medial rectus muscle and (via parasympathetic fibres) the sphincter pupillae muscle

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11
Q

Power of the eye

A

1/focal length

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12
Q

Layers of Retina

A
  1. Pigmented epithelium
  2. Photoreceptor layer
  3. Outer nuclear layer - cell bodies of rods & cones
  4. Outer plexiform layer - axons of rods & cones
  5. Inner nuclear layer - cell bodies of horizontal and bipolar cells
  6. Inner plexiform layer - axons, bipolar, amacrine, ganglion cells dendrites
  7. Ganglion cell layer - cell bodies
  8. Optic nerve layer - long axons of ganglion cells = optic nerve
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13
Q

Müller cells function

A
  • Long glial cells
  • Stretch almost the entire length of the retina
  • Function to maintain extracellular environment
  • Regulating K+
  • Remobe debris
  • Uptake of neurotransmitters
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14
Q

Properties of Rods

A

Function to detect light. More amount of rhodopsin than cones makes them more sensitive to light. They have vision in darkness, but low acuity = how clear you can see the image, because many rods synapse on each bipolar cell

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15
Q

Properties of Cones

A

Participates in color vision. Primarily located in the macula. Have high acuity due to one to one synapse with bipolar cells, especially in the fovea of the macula. Cones for red, blue and green colors.

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16
Q

Photoreception pathway

A
  1. 11-cis retinal
    Light
  2. All - trans retinal
  3. Metarhodopsin II
  4. Activation of transducin (G protein)
  5. Activation of phosphodiesterase
    - Conversion of cGMP to 5’GMP
  6. Decreased cGMP
  7. Closure of Na+ channels
  8. Hyperpolarization of photoreceptor membrane
  9. Decreased release of glutamate can lead to depending on the receptor type:
    - Ionotropic receptor: Decreased excitatory glutamate response = hyperpolarization of bipolar/horizontal cells
    - Metabotropic receptor: Decreased inhibitory glutamate response = depolarization of bipolar/horizontal cells
17
Q

Visual receptive fields: Center part

A

Photoreceptor cell that is directly in contact with the polar cell

18
Q

Visual receptive fields: Surround part

A

Cells that is indirectly touching a bipolar cell via a horizontal cell

19
Q

When [glutamate] decreases: Ionotropic receptors cause

A

Inhibition

20
Q

When [glutamate] decreases: Metabotropic receptor cause

A

Excitation

21
Q

Optic pathway

A
  1. Photoreceptor
  2. Optic nerve - optic chiasm - optic tract
  3. Lateral geniculate body
  4. Geniculocalcarine tract
  5. Occipital cortex