Physiology Of The Neuron Flashcards
Na
Extracellular- 145
Intracellular- 10
K
Extracellular- 4
Intracellular- 140
Ca
Extracellular: 2-2.5
Intracellular- <1
Mg
Extracellular- 2
Intracellular- 50
Cl
Extracellular- 105
Intracellular- 4
PO4
Extracellular- 2
Intracellular- 75
HCO3
Extracellular- 24
Intracellular- 10
Principle location of VGNAC
In axon
Concentrated in nodes of Ranvier
Absolute refractory period
Time when VgNaC are in the inactivated state
Examples of absolute refractory period
- Cardioplegic solution
- Succinylcholine
- Locals anesthetics
Action potential is what type of event
All or nothing
Most responsible for resting membrane potential
Leaky K channels
Most responsible for depolarization of axon
Diffusion of Na into ions
Most responsible for repolarization of axon
K diffusing out of cell