physiology of pain Flashcards

1
Q

define pain

A

unpleasant sensory and emotional experience associated with actual tissue damage or described as

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2
Q

processes in the physiology of pain

A

transduction
transmission
modulation
perception

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3
Q

transduction

A

translation of noxious stimulus into electrical activtiy at the peripheral nociceptor

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4
Q

transmission

A

propagation of pain signal as nerve impulses through the nervous system

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5
Q

modulation

A

modification/ hindering of pain transmisison in the nervous system

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6
Q

perception

A

conscious experience of pain causing physiological and behaviorual responses

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7
Q

how does pain begin

A

activation of nociceptors

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8
Q

how are nociceptors acitvated

A

by intense noxious stimuli

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9
Q

what are first order neurones

A

nociceptors which relay info to second order neurones in the CNS

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10
Q

how to nociceptors relay info

A

by chemical synaptic transmission

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11
Q

route of second order neurones

A

ascend the spinal cord in the anterolateral system

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12
Q

where do second order neurones terminbat

A

thalamus

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13
Q

subtypes of nociceptors

A

a and c fibres

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14
Q

a fibres

A

mechanical/ thermal nociceptors
thinly myelinated
mediate first or fast pain

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15
Q

c fibres

A

unmyelinated
respond to all noxious stimuli
mediate second/ slow pain

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16
Q

which fibre for stabbing, pricking sensation

A

a fibres

17
Q

which fibre for burning, throbbing, cramping, aching sensations

A

c fibres

18
Q

somatic pain

A

superficial- skin/ muscle or deep joints

19
Q

which type of pain sensation is somatic

A

throbbing or aching

20
Q

visceral pain

A

internal organs
less localised

21
Q

is nociceptive pain adaptive

A

yes

22
Q

is pathological pain adaptive

A

no, maladaptive

23
Q

maladaptive pain meaning

A

doesnt get better when tissue is fixed
so the pain is the problem not the damage

24
Q

adaptive pain meaning

A

helpful pain which promotes healing

25
Q

is inflammatory pain adaptive or maladaptive

A

adaptive !;p