Physiology of normal white blood cells Flashcards
Complete the diagram of haematopoiesis for lymphoid cells

Complete the diagram on haematopoiesis of myeloid cells

Name the 10 components of the immune system
- B cell
- T cell
- Large granular lymphocyte
- Mononuclear phagocyte
- Neutrophil
- Eosinophil
- Basophil
- Mast cell
- Platelets
- Tissue cells
Which cells make up adaptive immunity?
B cells and T cells
Which 7 components of the immune system are leucocytes?
- B cell
- T cell
- Large granular lymphocyte
- Mononuclear phagocyte
- Neutrophil
- Eosinophil
- Basophil
Which 3 components of the immune system are lymphocytes?
- B cell
- T cell
- Large granular lymphocyte
Which 7 components of the immune system are phagocytes?
- Mononuclear phagocyte
- Neutrophil
- Eosinophil
Which 3 components of the immune system are auxillary cells?
- Basophil
- Mast cell
- Platelets
Which 3 components of the immune system are granulocytes?
- Neutrophil
- Eosinophil
- Basophil
What is a normal leucocyte (neutrophil) count in adult?
7.3 x 103
Which 2 cells make up the majority of lymphocytes?
Which type of cell makes up 5% of lymphocytes?
B cells and T cells
Which lymphocytes do and do not have antigen specific receptors?
B cells and T cells DO have antigen specific receptors
NK cells DO NOT have antigen specific receptors
What is the morphology of basophils?
Lobed nuclei and heavily granulated cytoplasm
What is the function of basophils?
Function by releasing pharmacologically active substances from their cytoplasmic granules
Where do basophils circulate?
The blood
What sites are basophils recruited to and what is their role there?
Sites of allergic reactions or ectoparasite infection
Express FceRI
Allergen can bind to allergen-specific IgE bound to the cell surface of basophils causing degranulation of effector mediators
Complete the diagram of the morphology of a neutrophil

What type of cell is this?

Eosinophil
What is the morphology of eosinophils?
Have bilobed nuclei and granulated cytoplasm
Why are eosinophils motile phagocytic cells?
Can migrate from the blood into the tissues
Where are the majority of eosinophils located?
Tissues
Which sites in the body are eosinophils recruited too and what is their role there?
Recruited to sites of allergic reactions
Express FceRI upon activation
Granules containing toxins e.g. peroxidases
Attack parasites in GI, respiratory and genito-urinary tracts
Which cell is this?

Neutrophil
Which cell type is a polymorphonuclear cell?
Neutrophil




