Physiology I Flashcards
What term refers to the maintenance of nearly constant conditions in the internal environment and is the condition in which the body’s internal environment remains relatively constant within limits?
Homeostasis
An organism is said to be in homeostasis when its internal environment:
Contains the optimum concentraitons of ____, ______, _____ and _______
Has an optimal _______
Has an optimal ______ for the health of the cells
Gases, nutrients, ions and water
Temperature
Pressure
_______ is any stimulus that creates an imbalance in the internal environment
Stress
A change is some a parameter causes a response that results in a return of that parameter to normal. The response reverses the direction of the initial condition is refered to as what?
Negative feedback loop
What are the two characteristics of feedback loops?
Diminishes the original change
Stabilizing
_______ is the degree of effectiveness with which a control system maintains constant conditions
Gain
*** be sure to remember how to calculate gain
Small diameter axons transmit more ______ than large diameter axons
Slowly
_______ conduction is characterisitc of the myelinated axon but not the cell body of dendrites
Saltatory
What is the first thing that happens after the sodium ligand-gated channels open?
End-plate depolarization
During contraction of a skeletal muscle:
Actin filaments form the ____ bands which become ______ in width
I bands
Narrower
During contraction, the ____ band is equivalent to the length of the myosin filaments and doesn’t change in width
A band
The _____ band is the part of the A band that is not overlapped by the actin filaments and becomes ________
H band
Narrower
Skeletal muscle fibers and cardiac muscle fibers both have what 3 characteristics?
DHP channels on T tubules and Ryanodine receptors on sarcoplasmic reticulum
Sarcomeric arrangement
Multinucleated, peripheral nuclei
T tubules are found at the ends of the thick filaments
Two cisternae per T tubule
T tubules form triads with the sarcoplasmic reticulum
Sarcoplasmic reticulum is more extensive
Motor unit arrangement where one nerve fiber synapses with one or more skeletal muscle fibers
Are all characteristics of what type of muscle fiber?
Skeletal muscle fibers
Central, single nucleus per cell T tubules are found along the Z line There is one cisternae per T tubule T tubules form dyads with the sarcoplasmic reticulum SR is less extensive Muscle cells form a syncytium
These are all characterisitics of what type of cell?
Cardiac muscle fibers
There are 4 phases of fast action potentials in cardiac muscle action. What phase is considered resting potential?
Phase 4
During fast action potentials in cardiac muscle, what happens at phase 0?
Rapid depolarization
During fast action potentials in cardiac muscle what happens during phase 1?
Initial, incomplete repolarization
During fast action potentials in cardiac muscle what does phase 3 consist of?
Repolarization
What is the resting potential in cardiac muscle?
-85mV
Greater AP amplitude
More rapid rate of rise of phase 0
Larger cell diameter
Are characteristics of what type of cardiac muscle action potential?
Fast action potential
No fast sodium ion gates
Sunstroke of AP is due to calcium
Resting potential is close to -60mV
Amplitude is smaller
These are all characteristics of what type of cardiac muscle action potential?
Slow action potentials
How can stroke volume output be increased?
By increasing end diastolic volume
Or
By decreasing End systolic volume
How do you calculate ejection fraction?
Systolic volume (actual amount of blood ejected from the heart) / End diastolic volume (the amount of blood in the ventricle just before it contracts)
How do you calculate stroke volume?
(End diastolic volume (the amount of blood in the ventricle just before it contracts)) minus (End systolic volume (the amount of blood left in the ventricle after it has contracted))
What do P waves, QRS waves and T waves represent?
P waves= atrial depolarization
QRS waves= ventricular depolarization
T waves= ventricular depolarization
In regards to ECG vectors, what lead consists of the following characteristics?
Two electrodes on two arms
-R= negative
-L- positive
Direction of the lead = 0 degrees
Bipolar lead I