Physiology: Body fluid shift compartments

Question 1

What happens to cell volume in a hypertonic/hypotonic solution?

Answer 1

Hyper - decrease

Hypo - Increase

Question 2

How much body weight is water (TBW)

Answer 2

Male - 60%

Female - 50%

Question 3

How much of total body water is Intracellular and Extrecellular fluid?

Answer 3

Intracellular - 67%

Extracellular - 33%

Question 4

What does ECF contain?

Answer 4

Plasma - 20%
Interstitial fluid - 80%
lymph (negligible) + transcellular fluid (negligible)

Question 5

What is a good tracer of TBW, ECF and plasma?

Answer 5

TBW - 3H2O
ECF - Insulin
Plasma - Labelled albumin

Question 6

What are levels of Sodium in ICF and ECF?

Answer 6

ICF - 10

ECF - 140

Question 7

What are the levels of Potassium in ICF and ECF?

Answer 7

ICF - 140

ECF - 4.5

Question 8

What are the levels of Chlorine in ICF and ECF?

Answer 8

ICF -7

ECF - 115

Question 9

What are the levels of bicarbonate in the ICF and ECF?

Answer 9

ICF - 10

ECF - 28

Question 10

What are the main ions in the ECF?

Answer 10

Na+
Cl-
HCO3

Question 11

What are the main ions in the ICF?

Answer 11

K+
Mg2+
-vely charged proteins

Question 12

What does regulation of ECF play a part in?

Answer 12

Blood pressure regulation

Question 13

What alters the composition and volume of ECF?

Answer 13

Kidneys

Question 14

What 2 ions directly affect the functioning of all cells?

Answer 14

Sodium and Potassium

Question 15

What does potassium have a key role in?

Answer 15

Establishing a membrane potential

Question 16

What can an increase or decrease in K+ lead to?

Answer 16

muscle weakness - paralysis

Cardiac irregularities - cardiac arrest

Question 17

If the osmotic concentration of ECF increases, what happens?

Answer 17

Increase in ICF and decrease in ECF