Physiology Flashcards

1
Q

Why is blood considered to be a separate chamber?

A

chamber of its own, circulatory sytem

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2
Q

In which aspect is the blood volume especially important?

A

control of cardiovascular dynamics.

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3
Q

What is the average blood volume of an adult?

A

7 % of body weight, about 5 liters ,

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4
Q

what % of blood is plasma?

A

60%

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5
Q

Are the percentages of RBCs and plasma constant ?On what factors does it depend?

A

No,on gender,weight and other factors

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6
Q

The fraction of blood composed if RBCs is called?

A

Hematocrit( Packed RBC volume)

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7
Q

How is Hematocrit determined?

A

centrifuging in Hematocrit tube

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8
Q

What percentage of plasma remains entrapped between RBCS after centrifugation?

A

3 to 4 %

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9
Q

What are the Hematocrit values for male,female,anemic and polycythemic people?

A

male 0.40, female 0.36 , anemic 0.10,polycythemic can rise to 0.65

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10
Q

What happens in polycythemia?

A

excessive production of RBCS.

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11
Q

What is the major function of RBCs?

A

transport of Hb

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12
Q

Is there a possibility for Hb to circulate as a free protein normally?

A

Yes, in some animals

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13
Q

What are the other functions of RBCs?

A

carrying of carbonic anhydrase

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14
Q

Which reaction does carbonic anhydrase catalyse?

A

reaction of water and CO2

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15
Q

What makes blood transport enormous amount of CO2?

A

rapidity of carbonic acid formation

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16
Q

Which component of blood is an excellent acid-base buffer?

A

Hb

17
Q

which components of blood are most responsible for buffering power of blood?

A

RBCs

18
Q

What is the shape of RBC?

A

Biconcave disk

19
Q

What is diameter and thickness of RBC?

A

diameter 7.8 micrometers, thickness 2.5 micrometers at thickest point 1 micrometer at center

20
Q

What is volume of RBC?

A

90 to 95 cubic micrometers

21
Q

Can the RBC be deformed?

A

Its is basically like a ‘bag’ its is deformed when it squeezes through the capillaries.

22
Q

What do you think of the RBC cell membrane?

A

RBC has a great excess of cell membrane for quantity of material inside it. Deformation does not stretch it greatly so the cell doesn’t rupture unlike most of the other cells.

23
Q

What is the concentration of RBCs in blood?

A

male 5200000 per cubic ml (+-300000), female 4700000 per cubic ml (+-300000).

24
Q

People living at high altitude have —– no. of RBCs than normal.

A

greater