Physiology Flashcards
(24 cards)
Why is blood considered to be a separate chamber?
chamber of its own, circulatory sytem
In which aspect is the blood volume especially important?
control of cardiovascular dynamics.
What is the average blood volume of an adult?
7 % of body weight, about 5 liters ,
what % of blood is plasma?
60%
Are the percentages of RBCs and plasma constant ?On what factors does it depend?
No,on gender,weight and other factors
The fraction of blood composed if RBCs is called?
Hematocrit( Packed RBC volume)
How is Hematocrit determined?
centrifuging in Hematocrit tube
What percentage of plasma remains entrapped between RBCS after centrifugation?
3 to 4 %
What are the Hematocrit values for male,female,anemic and polycythemic people?
male 0.40, female 0.36 , anemic 0.10,polycythemic can rise to 0.65
What happens in polycythemia?
excessive production of RBCS.
What is the major function of RBCs?
transport of Hb
Is there a possibility for Hb to circulate as a free protein normally?
Yes, in some animals
What are the other functions of RBCs?
carrying of carbonic anhydrase
Which reaction does carbonic anhydrase catalyse?
reaction of water and CO2
What makes blood transport enormous amount of CO2?
rapidity of carbonic acid formation
Which component of blood is an excellent acid-base buffer?
Hb
which components of blood are most responsible for buffering power of blood?
RBCs
What is the shape of RBC?
Biconcave disk
What is diameter and thickness of RBC?
diameter 7.8 micrometers, thickness 2.5 micrometers at thickest point 1 micrometer at center
What is volume of RBC?
90 to 95 cubic micrometers
Can the RBC be deformed?
Its is basically like a ‘bag’ its is deformed when it squeezes through the capillaries.
What do you think of the RBC cell membrane?
RBC has a great excess of cell membrane for quantity of material inside it. Deformation does not stretch it greatly so the cell doesn’t rupture unlike most of the other cells.
What is the concentration of RBCs in blood?
male 5200000 per cubic ml (+-300000), female 4700000 per cubic ml (+-300000).
People living at high altitude have —– no. of RBCs than normal.
greater