Physiology Flashcards

1
Q

Name the 3 components of blood

A

Plasma, Buffy coat, RBC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the 3 main functions of blood

A

Transport - CO2 and O2
Maintenance of vascular integrity
Immunity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Where are the blood cells formed (and what is this called)

A

HAEMATOPOESIS occurs within the bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the 2 groups of stem cells known as

A

Myeloid and Lymphoid progenitor cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Name 3 main components of Plasma and 2 main components of Buffy coat

A

Plasma - Coagulation Factors, Albumin and Antibodies

Buffy coat - WC and platelets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Differentiation of Lymphoid Cells

A

Natural killer
T and B cells
Plasma Cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Differentiation of Myeloid Cells

A
Eosinophils
Basophils
Neutrophils
Mast cells
Erythocyte
monocyes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Where does B-Cell activation occur

A

Germinal Centres of the Secondary Lymphoid organs - Spleen and lymph nodes etc.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q
Normal Ranges for...
Hb (male)
Hb (female)
Platelets
WCC
A

Hb (male) - 135 - 170
Hb (female) - 120 - 160
Platelets - 150 - 400
WCC - 4 - 10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Name the 2 forms of Tissue in the spleen and what is their function

A

Red Pulp - where the Red cells are activated

White Pulp - Immune function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Give 3 potential Causes of Hypo and Hypersplenism

A

Hypo - Alcoholic Liver disease, Coeliac disease, HbSS

Hyper - Infection, Haem malignancy, haemolytic disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Name the elements and protein or a RBC and describe its structure

A

Enzymes, membrane and haemoglobin

Proteins = Alpha and Beta Spectin and Ankyrin

The RBC is made up 2 alpha chains (each with 2 genes = 4 total) and 2 Beta chains (each with 1 gene = 2 total) - these are the haem chains
the final product is haem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly