Physiology

Question 1

Glucagon is made by

Answer 1

Alpha cells in pancreas

Question 2

What s the function of glucagon

Answer 2

Glycogenolyis, gluconeogenesis

Lipolysis and ketone production

Question 3

Glucagon is inhibited by………..

Answer 3

Insulin, hyperglycemia and somatostatin

Question 4

What s the function of dopamine and TRH

Answer 4

Dopamine - prolactin and TSH

TRH + prolactin and TSH

Question 5

GnRH is supressed by

Answer 5

Hyperprolactinemia

Question 6

What s the function of Somatostatin

Answer 6

Somatostatin decreased GH and TSH

Question 7

Dopamine agonist like………….can be used in treatment of………….

Answer 7

Bromocriptine

Prolactinoma

Question 8

Dopamine antagonist like……………….stimulate………….

Answer 8

Antipsychotics
Estrogens (OCP and pregnancy)
Prolactin secretion

Question 9

Function of GH

Answer 9

Stimulates linear growth and muscle mass via IGF 1 (Somatomedin C) secretion by liver. |^ insulin resistance

Question 10

Excess secretion of GH can cause

Answer 10

Acromegaly in adult

Gigantism in children

Question 11

Whats the treatment of acromegaly

Answer 11

Treat with somatostatin analogs (ocreotide)

Question 12

Whats the function of Ghrelin

Answer 12

Stimulate hunger and GH release

Question 13

Ghrelin is produced by……….

Answer 13

By stomach

Question 14

Ghrelin can cause

Answer 14

Sleep deprivation and Prader Willi syndrome

Question 15

What s the function of leptin

Answer 15

Is satiety hormone

Question 16

Mutation of leptin gene can cause

Answer 16

Obesity

Question 17

What s the function of ADH

Answer 17

Regulates serum osmolarity (V2 receptors)
Blood pressure (V1 receptors)

Question 18

Action of ADH on serum osmolarity and urine osmolarity

Answer 18

Decrease serum osmolarity

And Increase urine omolality

Question 19

ADH level is…… in central DI, ………………or…“…………….in nephrogenic DI

Answer 19

Decreased

Normal or Increased

Question 20

Treatment for central DI and nocturnal enuresis

Answer 20

Desmopressin acetate (ADH analog)

Question 21

Mnemotechnics for cortisol function

Answer 21

Cortisol is a BIG FIB
Increase Blood pressure, Insulin resistance, Gluconeogenesis
Decrease Fibroblast activity, Inflammatory and Immune response, Bone formation

Question 22

Plasma Ca 2+ exists in 3 forms. Whats forms

Answer 22

Ionized (45 %)
Bound to albumine (40%)
Bound to anions (15 %)

Question 23

T3 function 4B?

Answer 23

Brain maturation
Bone growth
Beta adrenergic effect
Basal metabolic rate