Physiology 3.1 Flashcards

1
Q

What is the feeding centre?

A

This promotes feelings of hunger and the drive to eat.

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2
Q

What is the satiety centre?

A

This makes you feel full up, it suppresses the feeding centre.
It is insulin dependant.

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3
Q

What is the glucostatic theory?

A

The feeding and satiety centres are controlled by blood glucose levels.
High levels of blood glucose = + satiety centre, - feeding centre.

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4
Q

What is the lipostatic theory?

A

Fat stores determine food intake - controlling the feeding and satiety centres.
Increase in fat stores = +satiety centre, - feeding centre.

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5
Q

What hormone is released by fat?

A

Leptin - this depresses the feeding activity.

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6
Q

How many Scottish adults are overweight or obese?

A

2/3rds.

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7
Q

How do we use energy?

A

Cellular work - transporting molecules (non-voluntary).
Mechanical - Intracellularly (like movement of neurotransmitters down a nerve axon) or large scale - using skeletal muscle (voluntary).
Heat loss - Non-voluntary.

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8
Q

Which is the only voluntary form of energy output?

A

mechanical movement of skeletal muscle.

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9
Q

How much of our energy input is caused by heat loss?

A

Half of our energy.

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10
Q

What is metabolism?

A

Integration of all biochemical reactions in the body.

  1. Extracting nutrients in food
  2. storing that energy
  3. using that energy for work
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11
Q

What are the metabolic states of the body?

A

Absorptive, post-absorptive and starvation. The body usually flicks between the first 2.

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12
Q

What happens after eating?

A

The absorptive state - anabolic reactions. To store the nutrients we have just consumed.

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13
Q

What happens between meals and periods of not eating?

A

We enter the post-absorptive state - catabolic reactions. We break down our bodies nutrient stores and use them for energy.

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14
Q

How does the brain get its energy?

A

The brain can only use glucose. Except in starvation it can breakdown ketone bodies.

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15
Q

How does the rest of the body get its energy?

A

They prefer to use glucose, but can also use fatty acids or amino acids.

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16
Q

The brain gets first dibs on glucose in the blood.

A

Any glucose in the blood is automatically available to the brain.

17
Q

What is gluconeogenesis?

A

creation of glucose

18
Q

What is glycogenolysis?

A

Breakdown of glycogen.

19
Q

What is the normal blood glucose range?

A

4.2-6.3mM.

Usually 5mM.

20
Q

What is hypoglycaemia?

A

<3mM.

21
Q

How is blood glucose maintained?

A

Using the hormones glucagon and insulin.

22
Q

How much of the pancreas is endocrine?

A

Only 1%, the rest is exocrine.

23
Q

What are the endocrine cells of the pancreas called?

A

Islets of Langerhans.

24
Q

What are the cell types in Islets of Langerhans?

A

alpha - produce glucagon.
beta - produce insulin.
delta - produce somatostatin.
F cells - produce pancreatic polypeptide.