Physiology Flashcards
1
Q
How is fluid homeostasis managed?
A
- Inc osmolarity: Inc ADH secretion = retain H2O
- Low Osmolarity: Low ADH = Excrete H2O
- Inc vol: Low aldosterone, high ANP = Excrete Na + H2O
- Low vol: Inc aldosterone, low ANP = Retain Na + H2O
2
Q
How does ANP work?
A
- Responds to atrial stretch
- Inc Na & H2O excretion
- Inhibits renin & aldosterone release
- Inc GFR: afferent dilate, efferent constrict
3
Q
Where is the JGA?
A
Between afferent arteriole & DCT
4
Q
What are the types of cells in the JGA?
A
- Macula Densa: Sense reduced Na in DCT
- Granular: Sense reduced pressure in afferent wall
5
Q
What is the result of JGA being triggered?
A
- Renin release
- Afferent dilation
6
Q
A