Physiology Flashcards

1
Q

What is a neurohormone

A

When a neurone releases a hormone into the blood

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2
Q

What is a paracrine hormone

A

A hormone with local effect to its release

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3
Q

Name of hormone before it becomes functional

A

Prohormone

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4
Q

Name of cleaved ineffective hormone associated with insulin

A

C-peptide

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5
Q

What is a tropic hormone

A

A hormone which regulates release of another hormone

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6
Q

What does trophic mean

A

Hormone has an effect on growth

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7
Q

1 order disorder

A

Defect in hormone secreting cell

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8
Q

2nd order secretion

A

Little or too much tropic hormone from pituitary

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9
Q

3rd order

A

related to hypothalamic defect

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10
Q

Endocrine part of pancreases name

A

islets of langerhans

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11
Q

What cells secrete glucagon

A

alpha

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12
Q

What cells secrete insulin

A

Beta

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13
Q

What cells secrete somatostatin

A

delta

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14
Q

insulin stimulates what receptors in adipose and skeletal muscle cells

A

Glut-4

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15
Q

Effect of increased glucose on insulin and glucagon

A

Increases insulin

Decreases glucagon

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16
Q

Effect of amino acids on insulin and glucagon

A

Increases both

17
Q

What 2 things are needed for growth hormone to be effective

A

IGF-1

Thyroid hormone

18
Q

What stimulates release of IGF-1

A

Growth Hormone

19
Q

What organ releases IGF-1

20
Q

Effects of growth hormone

A

1- Increases blood glucose
2- inhibits insulin receptors on muscle and adipose
3- promotes lipolysis
4- increases amino acid uptake

21
Q

The 2 basic functions of thyroid hormone

A

Growth

Metabolism (catabolic of fat and protein)

22
Q

What condition produces antibodies which mimic TSH

A

Graves Disease

23
Q

Another word for adrenaline

A

Epinephrine

24
Q

What part of adrenal gland is neuroendocrine

A

Adrenal medulla

25
What part of adrenal gland is classic endocrine
Adrenal cortex
26
What is produced in Adrenal medulla
epinephrine norepinephrine Dopamine
27
What is produced in Adrenal Cortex
Mineralocorticoids-Aldosterone (Na and K balance) Glucocorticoids-Cortisol (maintain glucose levels in plasma) Sex Steroids- only very small portion, most made in gonads
28
What hormones increase Ca conc in plasma
Parathyroid hormone Calcitriol
29
What hormone decreases Ca conc in plasma
Calcitonin
30
How does PTH (parathyroid hormone) act
Stimulates osteoclasts to reabsorb bone Inhibits osteoblasts from depositing bone Increases secretion of phosphate in urine (Phosphate + Calcium needed for bone) Increases reabsorption of Ca in kidneys Stimulates kidney to produce calcitriol
31
How does calcitriol act
Increases Ca absorption in the intestine Increases Ca absorption in kidney Increases Phosphate absorption in kidney Mobilises Ca stores in bone
32
What 2 molecules does calcitriol cause the reabsorption of
Calcium Phosphate
33
What hormones Stimulate release of Ca from bone
Parathyroid Hormone (PTH) Calcitriol Cortisol
34
What does ACTH stimulate the release of
cortisol