Physiology Flashcards
What is a neurohormone
When a neurone releases a hormone into the blood
What is a paracrine hormone
A hormone with local effect to its release
Name of hormone before it becomes functional
Prohormone
Name of cleaved ineffective hormone associated with insulin
C-peptide
What is a tropic hormone
A hormone which regulates release of another hormone
What does trophic mean
Hormone has an effect on growth
1 order disorder
Defect in hormone secreting cell
2nd order secretion
Little or too much tropic hormone from pituitary
3rd order
related to hypothalamic defect
Endocrine part of pancreases name
islets of langerhans
What cells secrete glucagon
alpha
What cells secrete insulin
Beta
What cells secrete somatostatin
delta
insulin stimulates what receptors in adipose and skeletal muscle cells
Glut-4
Effect of increased glucose on insulin and glucagon
Increases insulin
Decreases glucagon
Effect of amino acids on insulin and glucagon
Increases both
What 2 things are needed for growth hormone to be effective
IGF-1
Thyroid hormone
What stimulates release of IGF-1
Growth Hormone
What organ releases IGF-1
Liver
Effects of growth hormone
1- Increases blood glucose
2- inhibits insulin receptors on muscle and adipose
3- promotes lipolysis
4- increases amino acid uptake
The 2 basic functions of thyroid hormone
Growth
Metabolism (catabolic of fat and protein)
What condition produces antibodies which mimic TSH
Graves Disease
Another word for adrenaline
Epinephrine
What part of adrenal gland is neuroendocrine
Adrenal medulla