Physiological Response To Inflammation

Question 1

State and explain the phases of wound healing after injury.

Answer 1

1. Haemostasis (platelets mobilisation, fibrin and proteoglycans formation. Stop bleeding)
2. Inflammation (neutrophils, lymphocytes, macrophages. Cleanse wound)
3. Proliferation (fibroblasts, collagen, eptithelial and endothelial cells)
4. Remodelling (scar maturation, collagen fibril cross linking)

Question 2

What are the cytokines produced in early in early inflammation?

Answer 2

TGF beta

PDGF