Physiological Changes In Geriatric Patients Flashcards
Elderly
65-74
Aged
75-74
Very old
> 85
Geriatric
> 65
Anatomical Upper respiratory
Edentulous
Loss of buccal fat
Decrease cervical spine extensions
Anatomical lower resp
Altered collagen network
Loss of elastic recoil
Incidenced alveolar airspace with reduced exchange
Anatomical MSK
Muscle loss
Vertebral column degeneration
Rib calcification
Increased chance of atelectasis impaired diaphragm function, loss of muscle mass and structural changes
Floop
Ristrictive pattern
Physiological resp
IRV reduced ERV REDU DECRE vital capacity High closing volume RV increase
Implications
High FRC with high closing volume which exceed FRC making patients prone to atelectasis
Central resp
Response to hypoxia and hypercabia is impaired with high sensitivity to sedatives
Implications
Decrease clearance of secretions Decrease mucociliary function Less efficient cough Reduced oesophagial motility Less effective protective upper airway reflexes
Neirexial
Avoid sedatives
Avoid intermediate and long acting neuromuscular Blockers
Neutralize stomach acide
Anaesthesia implications
Increase work of breathing Basal atelectasis Reduced baseline paO2 High A-a gradient Impaired cough and pharyngeal function Compromised compansation, early collapse, high risk of post-op pulmonary complications
Cardiac vascular
Atherosclerosis
Aeteril stiffening+ thickning
Arterial fibrosis
Arrhythmia AF
Increased afterload
Diastolic dysfunction
Labile blood pressure
Less sensitive to Badrenagic
Dystonia of aging
Anaesthesia implications
Other associated CVS conditions
Asymptomatic IHD
Calcific AS
Calcification of conduction sy
CNS
Decrease brain mass Loss of brain cells Low blood flow Cognitive dysfunction Impaired senses BP and temp control
Cognitive dysfunction diagnosis
Cognitive dysfunction pathophysiology
Inflammatory mediators
BBB dysfunction
Microglial activation resulting in apoptosisand and oncre pro inflammatory cytokine release
Cognitive dysfunction
Neuro cognitive disorders spectrum
Emergence delirium - immediately PACU
Postpartum DELIRIUM- 24-72hrs postop
Postop cognitive dysfunction - weeks - months post anaesthetic
Peripheral nerve detriation
Gene dysfunction with decrease mylination
Decrease conduction from reduced mylinated nerves
Change sensation : decrease spinal cord volume and bony degeneration
Autonomic
Limited adaptation to stress Decrease activity of parasympathetic and Sympathetic activation Decrease baroreceptor reflex sensitivity Slow and weak homeostasis Increased sympathetic tone
Avoid drugs with sympathomimetic
Pain control
Altered pin threshold
Reduced pain tolarance
Increased sensitivity to opioid
Risk of accumuation
Renal
GFR, Creat excretion reduced
Blunted RAAS
Prostate
UTI
Implications
Renal function assessment using forest or BUN may underestimate severity
Implications RASS
Ability to adjust volume and electrolyte imbalance
Renal