physio 6-9 Flashcards

1
Q

Which of the following, if changed, cause the ventricle to operate on another Frank-Starling
curve?

A

Troponin sensitivit
“troponin sensitivity is both a mechanism of inotropy and frank starling so this answer
could be for both along a curve or another curve”

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2
Q

Which of the following, if changed, cause the ventricle to move along a single Frank-Starling
curve?

A

Sarcomere length
“Frank starling= SV depends on preload which depends on VR > high VR > high EDV >
high stretch of cardiomyocytes = causes more blood to be ejected from the heart = like
stretched band the more u stretch the more it will be recoil”

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3
Q

What will increase in response to AL increase?
A. SV
B. ESV
C. Speed of ejection
D. Shortening of myocyte

A

B. ESV
“High AL= less blood can leave the heart > low SV = more blood left in the heart and the
higher the ESV”

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4
Q

On expense of which parameter does the ESV increase when increasing the afterload?
A. SV
B. preload
C. EDV

A

A. SV

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5
Q

Decrease of which will increase the preload?
A. Ventricular compliance
B. Afterload

A

A. Ventricular compliance
“When you decrease compliance a small change in volume will cause a large change in
pressure, EDP (preload) will increase. In this case preload is defined as EDP not EDV.”

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6
Q

which of the following parameters increases as a consequence of an increased afterload?
A. myocyte shortening
B. ejection fraction
C. end diastolic volume
D. speed of ejection
E. stroke volume

A

C. end diastolic volume
“When AL increases = SV decreases & more blood left in the heart increasing ESV= this
increases EDV in the next beat increasing preload so AL indirectly increases the EDV in the
2nd beat”

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7
Q

moves across along the same ventricular function curve.
A. Venous Return
B. Sarcomere Length
C. End systolic volume

A

B. Sarcomere Length
(all are counted)

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8
Q

Increases end diastolic volume and stroke volume
A. ventricular fibrillation
B. increased preload
C. increased afterload
D. increased inotropy
E. rapid ejection

A

B.increased preload

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9
Q

Increases end systolic volume and decreases stroke volume
A. ventricular fibrillation
B. increased preload
C. increased afterload
D. increased inotropy
E. rapid ejection

A

C. increased afterload

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10
Q

What increases myocardial oxygen consumption in aortic stenosis?
A. EDV
B. Stroke work

A

B. Stroke work
“More P work = high SW = high CW = high O2 consumption = low CE”

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11
Q

What is a characteristic of Frank-starling mechanism?
A. Increased efficiency
B. Decreased oxygen consumption
C. Decreased wall stress
D. Increased ejection fraction

A

B. Decreased oxygen consumption

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12
Q

What causes an increase in stroke volume secondary (or in the next beat) to an extrasystolic
beat?
A. decreased afterload
B. Increased contractility
C. Increased ESV
D. Frank-Starling mechanism (due to compensatory pause after extrasystolic beat)

A

B. Increased contractility
+
D. Frank-Starling mechanism (due to compensatory pause after extrasystolic beat)

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13
Q

What causes a negative inotropic effect?
A. Diastolic failure
B. Increased heart rate
C. Increased Afterload
D. Systolic failure

A

D. Systolic failure

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14
Q
A
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15
Q
A
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