Physical Examination of Urine (P & M) Flashcards
What are the characteristics of a normal urine (in terms of descriptions of color)?
Common descriptions include:
1) Straw
2) Pale yellow
3) Yellow
4) Dark yellow
How to properly examine a urine sx (for color examination)?
Examine the sx under a good light source, looking down through the container against a white bg
What is urochrome?
1) It is a pigment w/c is responsible for the yellow color of urine
2) It is a product of endogenous metabolism, and under normal conditions, the body produces it at constant rate
Who coined the name urochrome?
Thudichum
When is the name urochrome coined?
1864
The actual amt of produced urochrome is dependent on what?
It is dependent on the body’s metabolic state
When does increased amounts of urochrome happen?
1) Increased amounts produced in thyroid conditions and fasting states
2) Urochrome also increases in urine that stands at room temp
What is the characteristic of uroerythrin?
It is a pink pigment
When does uroerythrin become present in urine?
It is most evident in sxs that have been refrigerated
What is the result if uroerythrin is present in urine?
It results to precipitation of amorphous urates
What is urobilin?
It is the oxidation product of urobilinogen
What is the result if urobilin is present in urine?
It imparts an orange-brown color to urine that is not fresh
What is the indication if a urine has pink to reddish-brown sediment?
There’s a presence of large amt of amorphous urates
What is the indication if a urine is dark yellow or amber in color?
1) It signifies a normal concentrated urine (dehydrated)
2) Bilirubin is present
Is bilirubin normal to be seen in urine sx?
No
What is bilirubin?
It is an abnormal pigment and should not be present in urine
What test should be done if bilirubin is expected in a urine sx?
Foam test
How is foam test done?
If bilirubin is suspected, a yellow foam appears when the sx is shaken
What is the indication if a urine is yellow-orange in terms of color?
1) There is an occurrence of photo-oxidation of large amts of excreted urobilinogen to urobilin
2) Can be caused by phenazopyridine (Pyridium) or azo-gantrisin compounds to people who have UTIs
If there is a photo-oxidation of large amts of urobilinogen to urobilin, can a yellow foam appear when a sx is shaken?
No, a yellow foam does not occur when the sx is shaken
What is the result of foam test for the following conditions:
1) The color of urine is yellow-orange
2) Phenazopyridine (Pyridium) or azo-gantrisin compounds are present to people w/ UTIs
(+) yellow foam test [should be (-) yellow foam test?)
Is the presence of white foam normal in urine foam test?
Yes
What happens if urine is shaken vigorously for urine foam test?
A yellow colored foam at the upper portion of the sx occurs
What is the component that has the capability to interfere chemical analysis of urine?
Phenazopyridine (Pyridium)
What are the causes of (+) yellow colored foam (on upper portion of sx)?
1) High bilirubin content
2) Phenazopyridine (Pyridium) administration
What is the indication if a urine is pink to brown in color?
Presence of RBCs
The intensity (or change) in color of urine w/ presence of RBCs depends on what factors?
1) The amt of blood present in the sx
2) The pH of sx
3) Length of contact (of RBCs to sx?)
What is the indication if a urine is color brown?
Presence of oxidation of hgb to methemoglobin
When does oxidation of hgb to methemoglobin happen?
When RBCs present in sx are in acidic urine for several hours
What is the indication if a fresh urine is color brown?
May indicate glomerular bleeding
What is the cause of glomerular bleeding?
The conversion of hgb to methemoglobin
What are the 2 general characteristics of urine w/ RBCs (hematuria)?
1) Pink to bright red; cloudy or turbid; (smoky red)
2) Dark red to brown; cloudy or turbid
What is the indication of a urine under the following circumstances:
1) Pink to bright red in color
2) Cloudy or turbid
3) (Smoky red)
Presence of fresh RBCs from lower urinary tract (UT) bleeding
What is the indication of a urine under the following circumstances:
1) Dark red to brown in color
2) Cloudy or turbid
1) Presence of heavy bleeding in upper UT
2) Oxidation of hgb to methemoglobin in acidic urine
What are the clinical significances of hematuria?
1) Pyelonephritis and UTI
2) Urolithiasis (renal calculi)
3) Glomerulonephritis
4) Tumor (kidney or bladder cancer)
5) Trauma
6) Exposure to toxic chemicals and drugs (hydroxycobalamin and aspirin)
7) Strenuous exercise
8) Prostatis in male
9) STIs