Phsiologic Anatomy of the GI wall - Enteric NS Flashcards

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1
Q

measurement of individual muscle fibers in the GI tract

A

200-500 micrometers long and 2-10 micrometers in dm

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2
Q

Longitudinal muscle layer

A

extends longitudinally down the intestinal tract

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3
Q

circular muscle layer

A

bundle extends around the gut

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4
Q

gap junctions

A

found within each bundle

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5
Q

where can electric signals travel faster

A

along the length of the bundle

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6
Q

what separates each bundle of smooth muscle but not on its entirety?

A

loose connective tissue

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7
Q

How is branching lattice work of smooth muscle formed?

A

When muscle fibers fuse with one another at any joints

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8
Q

syncytium

A

when an action potential is elicited anywhere within the bundle masa, it generally travels in all directions in the muscle

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9
Q

How is the electrical activity of the GI smooth muscle?

A

Continuous but slow

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10
Q

2 basic type of electrical activity

A

Slow waves and spikes

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11
Q

Intensity in slow waves

A

between 5 and 15 mv

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12
Q

Frequency in the stomach, duodenum and ileum during slow waves

A

stomach (3/min)
duodenum (12/min)
ileum (8-9/min)

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13
Q

interstitial cells of cajal

A

electrical impulse in the slow waves

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14
Q

Normal resting membrane potential in the smooth muscle fibers of the gut

A

-50 to -60 mv

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15
Q

spike potentials frequency

A

1-10 spikes/s

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16
Q

the normal resting membrane potential

A

-56 mv

17
Q

depolarization

A

potential is less negative, muscle fibers more excitable

18
Q

hperpolarization

A

potential is more negative, fibers less excitable

19
Q

When do spike potential occur?

A

When resting membrane potential of the gi smooth muscle becomes more positive than -40 mv

20
Q

Calmodulin control mechanism

A

causes muscle contraction by activating the myosin filaments in the fiber

21
Q

Enteric nevrous system

A

-lies in the wall of the gut from esophagus to anus and controls gi movement and secretion

22
Q

2 plexus of the enteric nervous system

A

Myenteric plexus (Auebach’s) and submucosal plexus (meisner’s)

23
Q

Auerbach’s plexus

A

controls gi movements

24
Q

Meissners plexus

A

gi secretion and local blood flow