Photosensitivity - Idiopathic Sensitivity Disorders Flashcards
The most common form of Idiopathic photosensitivity
Polymorphous Light Eruption
Different morphologies of PLE
- Papular/Erythematopapular (Most common)
- Papulovesicular
- Eczematous
- Erythematous
- Plaque-like
PLE with pruritus only
and no eruption
PLE sine eruptione
Onset of PLE upon exposure
1 - 4 days
Which condition is more critical
in PLE in terms of sun exposure?
- Change in amount of exposure
- Absolute amount of exposure
Change in amount of sun exposure
Areas of involvement in PLE
- Face
- V-area of chest
- Neck
- Arms
A process in which an eruption improves
with continued sun exposure
Hardening
Unusual variant of PLE
in 5-12 y/o boys after sun exposure
on COLD BUT SUNNY days in the spring.
Juvenile Spring Eruption
Lesions of Juvenile Spring Eruption
Grouped small papules or papulovesicles on the helices.
Histopathology of PLE
- Perivascular T-cell infiltrate in the upper and middle dermis.
- Edema and endothelial swelling with occasional neutrophils
- Spongiosis and exocytosis in the epidermis.
Condition with PLE morphology but without the histological features
Pauci-inflammatory Photodermatitis
Sensitivity to UVA according to sex
WOMEN > men
Sensitivity to visible light based on sex
MEN > women
Differential diagnosis of PLE
- Lupus eryhthematosus
- Photosensitive drug eruptions
- Prurigo nodularis
- Photoallergic contact dermatitis
