PhotoaLlergic Flashcards
1
Q
Photo allergic substances
A
Sunscreens Fragrances Antibacterials Others ChemicalName Para aminobenzoic acid (PABA) Benzophenones 6 Methylcoumarin Muskambrette Dibromosalicylanilide Te t r a c h l o r o s a l i c y l a n i l i d e Bithionol Sul onamides Chlorpromazine
2
Q
DP
A
Epidermalspongiosis withlymphocyticin ltration
3
Q
dx
A
Historyo exposuretodrug,theallergiccon- tactdermatitispatterno theeruption,andits con nementtosun-exposedsites.Diagnosisis veri edbythephotopatchtest:Photoallergens are applied in duplicate to the skin and covered. A er24h,oneseto theduplicatetestsitesis exposed to UVA, while the other set remains covered. est sites are read or reactions a er 48 to 96 h. An eczematous reaction in the irradiated site but not in the nonirradiated site con rmsphotoallergytotheparticularagent tested
4
Q
tx
A
In severe cases, immunosuppression (azathio- prine plus glucocorticoids or oral cyclosporine) isrequired
