Phosphodiesterase inhibitor Flashcards
1
Q
What is Viagra?
A
Sildenafil citrate: PDE5 Inhibitor
2
Q
What is the Mechanism of action of Viagra?
A
When PDE5 inhibited, allows for increase in cGMP, since lesser is broken down
PKG activated more
Increase Vasodilation
Erectile Response
3
Q
What is the Side effect of Viagra?
A
May inhibit PDE6- leading to visual disturbances
4
Q
What potential ADR/ADE of Viagra?
A
Visual Disturbances
Drop in BP, Headache
Palpitations and cardiac Arrythmia
Bleeding
Nauseu and vommiting
Priapism
Hearing loss
5
Q
What is Rofulmuilast?
A
PDE4 Inhibitor
for Anit-COPD and Psioriasis
6
Q
A
7
Q
What is Roflumilast
A
PDE4 Specific :
Anti Pulmonary Hypertension COPD
8
Q
What is Apremilast?
A
PDE 4 Specific:
Psioarisis
9
Q
What is Ensifentrine?
A
PDE3/4 Inhibitor for Anti COPD
10
Q
A
