PHOSPHATE Flashcards
Extracellular phosphate
85%
Acts as part of
Hydrocyapetite
Essential components of
Teeth & bones
Required in
Glycogenolysis
Provide immediate source of
Glucose-6-phosphate
Acute renal faiulure
Hyperphosphatemia
Increased intake of PO2 among neonates w/ cow milk or laxative
Hyperphosphotemia
Lymphoblastic leukemia
Hyperphosphotemia
Intravascular hemolysis
Hyperphosphatemia
Neoplastic disorder
Hyperphosphatemia
Severe infections
Hyperphosphatemia
Intensive exercise
Hyperphosphotemia
DKA
hypophosphotemia
COPD
Hypophosphotemia
Vit, d deficiency or antacid use
Hypophosphotemia
Hyperparathyroidism
Hypophosphotemia
Increased renal excretion
Hypophosphotemia
Malignancy
Hypophosphotemia
Parathyroid hormone: hypocalcemia _ PTH secretion
Stimulates
PTH: hypercalcemia __ secretion of PTH
Suppresses
Calcitonin: hypercalcemia __ CT release
Stimulates
calcitonin: hypocalcemia __ ct secretion
Suppresses
Natural form produced in the skin from the action of sunlight
Vit D3/cholecalciferol
Most potent
1,25 OH2 vit D.
Other name for vit D2
Ergocalciferol
Needs by hydrolases to be active
Hydroxylation
Ref range neonate
1.45-2.91mmol/L
Ref range <15 yrs old
1.07-1.74mmol/L
Ref range adult
0.78-1.42mmol/L
Urine 24 hrs
13.0-42.0mmol/day
Phosphate specimen
Serum/heparinized plasma/24 hr urine
Oxalate, citrate, EDTA: not recommended
-hemolysis avoided
Methods for phosphorus
fiske & subbarow
Reduction of phosphomolybdate to molybdenum blue
Enzymatic method
Product of fiske & subbarow
Phosphomolybdate complex
Fiske & subbarow abs
340nm
Reduction abs
600-700nm