Pheromone Processing - Vertebrates Flashcards
What are the 2 distinct pathways for vertebrate pheromone processing?
MOE to MOB
VNO to AOB
OSNs move through this bone structure to get to the brain
Cribiform plate
Describe zone to zone projection of the olfactory bulb
Zones on the olfactory epithelium correspond to distinct zones on the olfactory bulb
In general, the main olfactory bulb processes (1) information
Olfactory
In general, the accessory olfactory bulb processes (1) information
Pheromone
True or false: there are multiple olfactory receptors within a given zone of the olfactory epithelium
True, but a given receptor is present in that zone only
What are the output neurons of the olfactory bulb? (2)
Mitral and tufted cells
Which 2 types of neurons are responsible for lateral inhibition of olfactory bulb output neurons?
Granule cells and periglomerular cells
Periglomerular cells synapse to (1) dendrites
Primary
Granule cells synapse to (1) dendrites
Secondary
What neurotransmitter is released by granule and periglomerular cells?
GABA
What neurotransmitter is released by mitral and tufted cells?
Glutamate
What are 2 factors which influence where a pheromone or odorant is processed within the vertebrate olfactory map?
- Carbon chain length
- Position (ortho, para, meta) of the side chain
Describe the importance of coincidence detection in the vertebrate olfactory system
Some neurons of the olfactory cortex need coincidence of several activated glomeruli to get a response – in this way, this is a form of pre-processing and is similar to combinatorial coding