phentermine/topiramate ER Flashcards
1
Q
brand name
A
qsymia
2
Q
MOA
A
NE-releasing agent (phentermine)
GABA receptor modulation (topiramate)
3
Q
dose
A
starting dose: 3.75/23 mg PO QD for 2 weeks
Recommended dose:
7.5-46mg PO QD
Escalation dose :
11.25/69 mg PO QD
Maximum dose
15.92 mg PO QD
4
Q
contradiction
A
- pregnancy and breastfeeding (topiramate teratogencity)
- hyper thyroidism
- acute angle-closure glaucoma
- concomitant MAOI use (within 14 days
5
Q
monitor for
A
increased heart rate
depressive symptoms or worsening of depresson
hypokalemia
acute kidney stone
