PHASMIDS (TRICHINELLA SPIRALIS, TRICHURIS TRICHURA, CAPILLARIA) Flashcards
Causes trichinosis, trichiniasis
discovered at autopsy in London
Parasite of carnivorous/omnivorous animals
trichinella spiralis
TRICHINELLA SPIRALIS
Adult
-> male measures 1.6x0.4 mm
->female measures 3.5x0.6 mm
->threadlike
-> with __________
stichosome
TRICHINELLA SPIRALIS
measures 1300 microns
maybe lodged in various foci (brain, heart, body cavities_
encyst/developed only in ______
skeletal muscle
TRICHINELLA SPIRALIS
REPRODUCTION
->after mating, males are dislodged from the _____-
-> femal burrows deeply to the mucosa (_________ to ________)
-> female dies after passing the larva
mucosa
duodenum to cecum
TRICHINELLA SPIRALIS
____ Larva/Gram of body muscle = death
FIVE
TRICHINELLA SPIRALIS
Gold standard: ___________
Serological test: ________
Muscle biopsy
ELIZA
TRICHINELLA SPIRALIS
TREATMENT:
__________: expels the adult worm and no effect on larva
__________: kills the larva and used for 2 weeks
Thiabendazole
Mebendazole
TRICHURIS TRICHURA
-egg
->___________ shaped
->prominent_______ on both ends
->requires _____ days for embryonation in the soil
barrel shaped
prominent bipolar mucus plugs
passed in the feces in fertilized unsegment stage
requires 10-14 days for embryonation
TRICHURIS TRICHURA
-> mode of infection - ___________
ingestion of fully embryonated egg
TRICHURIS TRICHURA
—-> habitat ________
colon
TRICHURIS TRICHURA
Direct fecal smear
<___ eggs/smear = light infection
>___ eggs/smear=heavy infection
10, 50
TRICHURIS TRICHURA
Treatment
Mebendazole (100 mg, 2x/day for 3days)
CAPILLARIA
EGGS:
1. __________
-yellow,peanut shaped
-thick shelled with straiations
-with flattened bipolar plug
2. _______________
thinshelled
without bipolar plugs
with segmentations
embryonated form
embryonate in 10-14 days
developed into _________ in the fish
typical egg
atypical egg
infective stage
