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Phase 2a JB > Phase 2 Drug List > Flashcards

Phase 2 Drug List Flashcards

1
Q

Aciclovir - Category

A

Antiviral

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2
Q

Aciclovir - Reason

A

Herpes simplex and Varicella zoster infections

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3
Q

Aciclovir - Mechanism

A

Competitively inhibits viral DNA polymerase to prevent viral DNA replication

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4
Q

Adenosine - Category

A

Anti-arrhythmic

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5
Q

Adenosine - Reason

A

Emergency management of superventricular tachycardia (SVT)

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6
Q

Adenosine - Mechanism

A

Acts as an agonist to reduce production of cAMP. This causes K+ hyperpolarisation in AV node cells which slows conduction

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7
Q

Adrenaline - Category

A

Alpha & Beta Adrenergic Agonist

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8
Q

Adrenaline - Reason

A

Anaphylaxis

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9
Q

Adrenaline - Mechanism

A
  1. α adrenoceptor activation - peripheral vasoconstriction
  2. β1 adrenoceptor activation - positive chronotropic and inotropic effects
  3. β2 adrenoceptor activation - bronchodilatation
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10
Q

Alendronate - Category

A

Bisphosphonate

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11
Q

Alendronate - Reason

A

Prophylaxis and treatment of osteoporosis, Paget’s disease

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12
Q

Alendronate - Mechanism

A

Impairs osteoclast bone resorption by adsorbing onto hydroxyapatite crystals. Promotes osteoclast apoptosis

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13
Q

Allopurinol - Category

A

Xanthine oxidase inhibitor

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14
Q

Allopurinol - Reason

A

Prophylaxis of gout and uric acid renal stones

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15
Q

Allopurinol - Mechanism

A

Inhibits oxidation of xanthine to uric acid, reducing concentration of insoluble uric acid in tissues

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16
Q

Amiodarone - Category

A

Anti-arrhythmic

17
Q

Amiodarone - Reason

A

Cardiac dysrhythmias, including - AF, Atrial flutter, Ventricular tachycardia

18
Q

Amiodarone - Mechanism

A

Na, Ca and α adrenoceptor inhibitor. Prolongs cardiac action potential (> QT interval)

Phase 2a JB (1 decks)

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