Phase 1 and 2 Reactions Flashcards
1
Q
Reduction
A
Phase 1
2
Q
Hydrolytic cleavage
A
Phase 1
3
Q
Alkylation (Methylation)
A
Phase 1
4
Q
Dealkylation
A
Phase 1
5
Q
Ring Cyclization
A
Phase 1
6
Q
N-Carboxylation
A
Phase 1
7
Q
Dimerization
A
Phase 1
8
Q
Transamidation
A
Phase 1
9
Q
Isomerization
A
Phase 1
10
Q
Decarboxylation
A
Phase 1
11
Q
Glucuronidation
A
Phase 2
12
Q
Sulfation
A
Phase 2
13
Q
Acetylation
A
Phase 2
14
Q
Amino Acid Conjugation
A
Phase 2
15
Q
Glutathione Conjugation
A
Phase 2
16
Q
Fatty Acid Conjugation
A
Phase 2
17
Q
Enzyme of Glucuronidation
A
UDP-Glucuronosyltransferase
18
Q
Enzyme of Sulfation
A
Sulfotransferase
19
Q
Enzyme of Acetylation
A
Acetyltransferase
20
Q
Enzyme of Glutathione Conjugation
A
Glutathione-S-transferase
21
Q
Oxidation
A
Phase 1
