Phase 1 and 2 Reactions Flashcards

1
Q

Reduction

A

Phase 1

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2
Q

Hydrolytic cleavage

A

Phase 1

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3
Q

Alkylation (Methylation)

A

Phase 1

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4
Q

Dealkylation

A

Phase 1

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5
Q

Ring Cyclization

A

Phase 1

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6
Q

N-Carboxylation

A

Phase 1

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7
Q

Dimerization

A

Phase 1

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8
Q

Transamidation

A

Phase 1

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9
Q

Isomerization

A

Phase 1

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10
Q

Decarboxylation

A

Phase 1

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11
Q

Glucuronidation

A

Phase 2

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12
Q

Sulfation

A

Phase 2

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13
Q

Acetylation

A

Phase 2

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14
Q

Amino Acid Conjugation

A

Phase 2

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15
Q

Glutathione Conjugation

A

Phase 2

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16
Q

Fatty Acid Conjugation

A

Phase 2

17
Q

Enzyme of Glucuronidation

A

UDP-Glucuronosyltransferase

18
Q

Enzyme of Sulfation

A

Sulfotransferase

19
Q

Enzyme of Acetylation

A

Acetyltransferase

20
Q

Enzyme of Glutathione Conjugation

A

Glutathione-S-transferase

21
Q

Oxidation

A

Phase 1