Pharyngitis

Question 1

Pharyngitis: Streptococcus pyogenes

Characteristics-

Answer 1

Gram-positive cocci in pairs or chains
Catalase negative
Beta-hemolytic on blood agar plate

Question 2

Pharyngitis: Streptococcus pyogenes

Virulence factors

Answer 2

M Protein
-Antiphagocytic
-Antigenic variation
SPE: Streptococcal pyrogenic exotoxins
-Encoded by phage
Many Enzymes

Question 3

Pharyngitis: Streptococcus pyogenes

Modes of transmission

Answer 3

Respiratory droplets

Question 4

Pharyngitis: Streptococcus pyogenes

Symptoms

Answer 4

Abrupt onset fever, sore throat with exudate, may have abdominal pain, nausea, vomiting

Question 5

Pharyngitis: Streptococcus pyogenes

Potential complications

Answer 5

Strawberry tongue
Sandpaper rash (starts on face then spreads to body, never on palms or soles)
Rheumatic fever (M protein cross reaction with heart and joints)